期刊文献+

肿瘤过继性细胞免疫治疗 被引量:4

下载PDF
导出
摘要 目前,肿瘤的细胞免疫治疗成为国内外研究的热点问题。其中,在过继性细胞免疫治疗(adoptive cellular immunotherapy,ACI)研究方面取得了很大成效。随着对人类免疫系统的认识和肿瘤发生机制的深入研究,肿瘤的免疫治疗的疗效不断得到提高,特别是在过继性细胞免疫治疗中,利用近代的转基因技术和细胞培养技术等,使得利用细胞免疫疗法彻底治愈肿瘤成为可能,本文将就肿瘤和免疫的关系、过继性细胞免疫治疗存在的优缺点及研究进展做一综述。
作者 陈勇伟 王坚
出处 《医学研究杂志》 2014年第9期161-165,共5页 Journal of Medical Research
  • 相关文献

参考文献4

二级参考文献44

  • 1杨文锋,于金明,左文述,王善政.食管癌组织中共刺激分子与白介素-10 mRNA的表达[J].中华肿瘤杂志,2006,28(10):762-765. 被引量:9
  • 2Michael R. Verneris,Martin Kornacker,Volker Mail?nder,Robert S. Negrin.Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis[J]. Cancer Immunology, Immunotherapy . 2000 (6)
  • 3Richard L. Kradin,Lenora A. Boyle,Frederic I. Preffer,Ronald J. Callahan,Martha Barlai-Kovach,H. William Strauss,Steven Dubinett,James T. Kurnick.Tumor-derived interleukin-2-dependent lymphocytes in adoptive immunotherapy of lung cancer[J]. Cancer Immunology Immunotherapy . 1987 (1)
  • 4Frankel TL,Burns WR,Peng PD,et al.Both CD4and CD8T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosi-nase. J Immunol . 2010
  • 5Koya RC,Mok S,Comin-Anduix B,et al.Kinetic phases of distribution and tumor targeting by T cell receptor engi-neered lymphocytes inducing robust antitumor responses. Proceedings of the National Academy of Sciences of the United States of America . 2010
  • 6Duval L,Schmidt H,Kaltoft K,et al.Adoptive transfer of allogeneic cytotoxic T lymphocytes equipped with a HLA-A2restricted MART-1T-cell receptor:a phaseⅠtrial in meta-static melanoma. Clinical Cancer Research . 2006
  • 7Warren EH,Fujii N,Akatsuka Y,et al.Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantationwith T cells specific for minor histocompatibility antigens. Blood . 2010
  • 8Khammari A,Labarrire N,Vignard V,et al.Treatment of metastatic melanoma with autologous Melan-A/MART-1-specific cytotoxic T lymphocyte clones. Journal of Investigative Dermatology . 2009
  • 9Casalegno-Garduo R,Schmitt A,Yao J,et al.Multimer technologies for detection and adoptive transfer of antigen-specific T cells. Cancer Immunology Immunotherapy . 2010
  • 10Geldmacher A,Freier A,Losch FO,et al.Therapeutic vac-cination for cancer immunotherapy:antigen selection and clinical responses. Hum Vaccin . 2011

共引文献38

同被引文献40

引证文献4

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部