乙型肝炎后肝硬化反复发作的影响因素探讨

Investigation on influencing factors of recurrent attacks in cirrhosis after hepatitis B

目的探讨乙型肝炎后肝硬化反复发作的影响因素。方法回顾性分析我院2012-2013年收治的70例乙型肝炎后肝硬化患者的资料,按照患者复发次数分为反复复发组（观察组,38例）和稳定组（对照组,32例）,从患者的一般情况、生活方式及治疗方式等方面对两组患者进行比较,总结乙型肝炎后肝硬化反复复发的高危因素。结果单因素分析显示,影响慢性乙型肝炎肝硬化患者复发的因素有家族史、精神刺激、肝损药物、过度劳累、饮酒、甜食摄入、手术创伤、HBV-DNA定量高、病程等。结论影响乙型肝炎肝硬化患者反复发作的因素多样,有效对高危因素进行消除并对原发病进行积极治疗,在乙型肝炎性肝硬化反复发作中有重要意义。

Objective To explore the influence factors of recurrent attacks of cirrhosis after hepatitis B. Methods The data of 70 patients with cirrhosis after hepatitis B which treated at 2012-2013 years were analyzed retrospectively,and according to recurrence occurs in patients with relapses into two groups（observation group,38 cases） and a stable Group（control group,32 cases）.From the patient＇s general condition,lifestyle and treatment methods to compare two groups of patients,and summarized risk factors for cirrhosis after hepatitis b recurrence occurs. Results Univariate analysis showed that factors influencing recurrence of liver cirrhosis in chronic hepatitis B patients have a family history of liver function,mental stimulation,drugs,overwork,intake of alcohol,sweets,surgical trauma,high HBV,the course,etc. Conclusion Influencing factors of relapse in patients with cirrhosis of hepatitis B is vary,and to eliminate risk factors and to active treatment of the primary disease of recurrent attacks of cirrhosis in hepatitis B is important.