常州市103例新生儿先天性心脏病随访分析

Follow-up of 103 infants with congenital heart disease in Changzhou

目的探讨建立符合中国国情的新生儿先天性心脏病(CHD)筛查、评估、干预体系。方法 2011年5月1日至2013年4月30日期间,对常州市妇幼保健院出生的16 070名新生儿进行CHD筛查及诊断,并对CHD新生儿定期随访至1岁。结果发现CHD 103例,发生率0.641%。CHD构成类型前三位是室间隔缺损(VSD,0.205%)、动脉导管未闭(PDA,0.174%)、房间隔缺损(ASD,0.10%)。103例CHD完成1年随访94例、失访9例,其中小型VSD、ASD及早产儿PDA闭合率高,部分严重CHD及有并发症患儿已手术治疗,其余未愈者仍在随访中。结论常州地区新生儿CHD发病率处于中国平均水平,对CHD患儿进行系统随访能有助于提高CHD患儿的生存质量。

Objective To establish a system of the screening, evaluation and intervention of congenital heart disease （CHD） in China. Methods All infants （16070） born in Changzhou Maternal and Child Health Hospital from May 1st 2011 to April 30th 2013 were screened for CHD. The infants with CHD were followed up till 1 year of age. Results One hundred and three infants were diagnosed with CHD, and the incidence rate was 0.641%. The top three CHD types in incidences were VSD （0.205%）, PDA （0.174%） and ASD （0.10%）, respectively. In these infants, 94 cases were followed-up and 9 cases were lost. The incidence of small gapped VSD, ASD and premature PDA were high. Some infants with serious CHD were subjected to surgery, and others were still followed up. Conclusions The incidence of CHD in Changzhou is comparable with that in the whole country. The follow-up can improve the life quality of CHD infants.