2002--2012年人和动物李斯特菌感染报告数据流行病学分析

Epidemiology of listeriosis infection in humans and animals,China,2002-2012

目的调查国内近11年来单核细胞增生性李斯特菌所引起的人及动物李斯特菌病的流行现状,为李斯特菌病的预防和控制提供理论依据。方法利用检索工具(系统)检索文献信息的方法收集我国2002-2012年李斯特菌病的文献报告资料,并对各个文献资料中李斯特菌病的临床特征与流行病学信息进行统计分析。结果本文所统计的李斯特菌感染病例涉及到全国27个(79%)省。共统计动物单核细胞增生性李斯特菌感染报道次数123次,其中猪感染报道次数最多(39%),次之为羊;感染类型以中枢神经系统感染最多(72%)。人李斯特菌感染报道病例共计84例,其中非围产期病例占35%,围产期病例占65%,以败血症症状居多(51%)。结论 2002-2012年间,每年均有人和动物李斯特菌病的发生,且报告病例涉及全国大部分省,提示应加强人及动物李斯特菌病的预防和控制。

The prevalence of human and animal listeriosis for nearly 11 years in China was investigated in this study. The literature information about listeriosis in China from 2002 to 2012 was collected through retrieval system to make clinical and epidemiological statistical analysis of listeriosis. Cases of listeriosis were reported in 27 （79 %） provinces of China. The re- sult showed that animal listeriosis was reported for 123 times, among these reports, most were from pigs （39%）, and the sheep was in second place. Central nervous system infection was the main clinical manifestation of listeriosis in animals （72 %）. For human listeriosis, 84 clinical cases of listeriosis were reported, including 35 % cases in non-perinatal stage and 65 % cases in perinatal stage. The main clinical manifestation of listeriosis was septicemia （51%）. According to the result of investigation about listeriosis based on literatures information, Listeria monocytogenes caused humans and animals listeriosis annually, which were reported in most provinces of China. The epidemic characteristics for listeriosis suggested that it was essential to strength- en the prevention and control of listeriosis.