摘要
三氟甲烷在一定条件下会较容易地脱去H,形成活泼的二氟卡宾,可以方便地在医药、农药及特殊化学品中间体内引入三氟甲基和二氟甲基,得到有着特殊功效的含氟化合物。开发三氟甲烷可以节约生产成本,消除环境危害,更可以作为一种新型氟化试剂,在化工、医药、农药展开多种新颖应用。
Trifluoromethane under certain conditions will be form difluorocarbene by remove a H, activation for the synthesis of trifluoromethylated or difluoromethylated intermediates, obtain valuable fuctionalized organic compounds. Available to treat trifluoromethane, it would be economically and environmentally more sustainable to feed stocks for production of novel fluoride applications in pharmaceutical, agrochemical and specialty materials industries.
出处
《有机氟工业》
CAS
2014年第3期46-54,共9页
Organo-Fluorine Industry
关键词
三氟甲烷
三氟甲基化
二氟甲基化
含氟烃
trifluoromethane
trifluoromethylation
difluoromethylation
hydrofluorocarbon