综合干预对肿瘤患者骨髓抑制期医院感染的预防作用

Effect of comprehensive intervention on prevention of nosocomial infections in tumor patients during bone marrow suppression

目的研究分析综合干预对肿瘤患者Ⅳ度骨髓抑制期医院感染的预防作用,以降低医院感染率。方法选取2011年1月-2013年4月在医院进行治疗的84例肿瘤Ⅳ度骨髓抑制期患者为研究对象,将其随机分为对照组(常规干预组)42例和观察组(综合干预组)42例,对两组患者不同骨髓抑制时间及各部位感染率进行比较,数据采用SPSS14.0软件进行统计处理。结果总感染率观察组为4.76%,明显低于对照组的23.81%,且其中不同抑制时间及各部位感染率也均低于对照组,差异有统计学意义(P<0.05)。结论综合干预可有效预防控制肿瘤Ⅳ度骨髓抑制期患者的医院感染率,对于该类患者的临床应用价值较高。

OBJECTIVE To study the effect of comprehensive intervention on prevention of nosocomial infections in the tumor patients during the bone marrow suppression Ⅳ so as to reduce the incidence of nosocomial infections . METHODS A total of 84 bone marrow suppression Ⅳ tumor patients who were treated in the hospital from Jan 2011 to Apr 2013 were enrolled in the study and randomly divided into the control group （the conventional intervention group ） with 42 cases and the observation group （the comprehensive intervention group） with 42 cases ,then the bone marrow suppression time and the incidence of infections were observed and compared between the two groups of patients ,and the data were statistically analyzed by using SPSS140 .0 software .RESULTS The total infection rate of the observation group was 4 .76% ,significantly lower than 23 .81% in the control group;the different suppression time and the incidence of infections of different sites of the observation group were also lower than those of the control group ,and there was significant difference （P〈 0 .05） .CONCLUSION The comprehensive intervention may contribute to the control of nosocomial infections in the bone marrow suppressionⅣ tumor patients and has great value in clinical value .