皮质下动脉硬化性脑病患者血清hs-CRP测定的价值研究

Clinical value C-resposive protein in serum in patients with subcortical arteriosclerotic encephalopathy

目的分析皮质下动脉硬化性脑病(SAE)患者血清hs-CRP测定的临床价值。方法 SAE患者90例为观察组,同期健康志愿者90例作为对照组,对比两组血清hs-CRP水平;患者按病情程度分为轻、中、重,对比观察各组间hs-CRP水平。结果观察组平均血清hs-CRP水平显著高于对照组,不同程度病情间的hs-CRP水平亦有明显差异,程度越严重指标水平越高,差异均有统计学意义(P<0.05)。结论 SAE患者血清hsCRP水平相比正常人明显升高,且随着病情发展程度而逐渐升高,与病情之间有着密切的关系。

Objective To study sigificance of CRP level in patients with subcortical arteriosclerotic encephalopathy（SAE）. Methods 90 SAE patients and 90 health cases were included. Patients were divided into three subgroups： mild group, moderate group and severe group. Hs-CRP level was compared among these three subgroups. Results The serum hs-CRP level in SAE group were higher than it in the control group（P〈0.05）. The significant difference were showed in different SAE subgroups（P〈0.05）. Conclusion The serum level of hs-CRP was significantly higher in patients with SAE and was associated with disease severity.