药学服务干预对高脂血症患者用药依从性、治疗效果及颈动脉粥样斑块的影响分析

Influence of Pharmaceutical Care on Medication Compliance and Treatment Effect and Carotid Atheromatous Plaque in Patients with Hyperlipidemia

目的探讨药学服务干预对高脂血症患者用药依从性、治疗效果及颈动脉粥样斑块的影响分析。方法确诊为高脂血症且有颈动脉粥样斑块的患者120例随机分为药学干预组(简称干预组)60例,对照组60例。干预组患者按照既定的药学服务方案进行干预,对照组不施行干预措施。分别于治疗前及治疗后一年内采用问卷方式进行用药依从性的测评,采空腹静脉血检查血脂;行颈动脉彩超以了解斑块数量、面积并采用Crouse方法进行斑块积分。结果药学服务干预组患者的用药依从性,血脂治疗的效果明显优于对照组患者。颈动脉粥样斑块积分显示两组患者在干预前后无显著差异,但是干预组有粥样斑块稳定的趋势。结论药学服务干预有利于提高高脂血症伴颈动脉粥样硬化患者用药依从性,有效地控制血脂在适当水平。

OBJECTIVE To explore the influence of pharmaceutical care on medication compliance and treatment effect and ca- rotid atheromatous plaque in patients with hyperlipidemia. METHODS One hundred and twenty Hyperlipidemia patients with carotid atheromatours plaque were stochastically divided into pharmaceutical intervention group and control group. Each group had 60 exam- ples. The intervention group received pharmareeutical care, while the other group didn＇ t do it. Medication compliance were assessed with questionnaire in this two groups before and within one year after treatment. Lipids was tested with fasting blood. The quantity and area of plaque were known by carotid color uhrasonography and the points were accumulated with the method of Crouse. RESULTS Compared with the control group, the intervention group was better in medication compliance and treatment effect. There was no signifi- cant difference in the points of carotid atheromatous plaque between the two groups but the stable trend of carotid atheromatous plaque can be seen in the intervention group. CONCLUSION Pharmaceutical care can significantly improve compliance with therapy and effectively control lipids of patients with hyperlipidemia and carotid atheromatous plaque.