摘要
本文对某PVC厂生活区空气VC污染状况及人群健康效应进行了调查,结果表明:空气质量指数(I_1)>1.50,空气质量属中度污染,此时氯乙烯(VC)≥0.17mg/m^3,10～14岁儿童血清溶菌酶(S-LZM)活性明显增高(12.34μg/ml,萤光法);而成人的S-LZM活性也增高(15.31μg/ml,比浊法),且T细胞转化率明显降低(72.9％),人群出现免疫效应;VC>4.0mg/m^3(I_1>2.0),空气质量属极重污染,成人染色体总断裂率明显增高(5.6％、G显带),呈现细胞遗传毒性;VC>25.0mg/m^3时,SCEs达9.08。并且发现效应有随接触VC量的增加而加重的趋势。研究还证明:I法评价空气环境质量比较合理,G显带染色体分析术对致突变物的环境流行病学调查有实用性。
The monitoring results showed that the air Quality Index (I_1>1.50) and the air was at mid- dle pollution level when the air vinyl chloride (VC) concentration was≥0.17mg/m^3. The serum lysozyme (S-LZM) activity of children aged 10 to 14 was 12.34ug/ml by fluorescence assay, and of the adult living in was (15.31ug/ml by turbidimetry) the area The T-cell transformation rate of the ad- ult (72%) were also found decreased significantly At this air pollution level, the immune effects ca- used by pollution could be detected. When VC was 4.0mg/m^3 (I_1>2.0), the air quality was at extre- me pollution level and the total chromosome brea- kage rates of the adult (15.6% G-banding) increased significantly, in which, the VC toxic effect on ce- llular heritage could be observed. When air VC was >25.0mg/m^3, the sister chromosome exchanges of the adult increased to 9.08. The study also sugges- tes that the air quality evaluated with I method was comparatively suitable and the chromosome G- banding analysis is availbe on environment epidem icological survey.
关键词
空气污染
氯乙烯
人群健康
Air pollution
Vinyl chloride
Serum lysozyme
Total
chromosome breakage rate
