高通量透析对尿毒症患者顽固性高血压的影响

Effects of high-flux dialysis on resistant hypertension in patients with uremia

目的:探讨高通量透析对尿毒症患者顽固性高血压的影响。方法:将尿毒症顽固性高血压患者30例随机均分为观察组和对照组。对照组采用低通量透析器,观察组采用高通量透析器。每周透析时间均为12 h,治疗12周,观察2组治疗前后收缩压、舒张压及平均动脉压的变化。结果:观察组治疗12周后收缩压、舒张压及平均动脉压降低程度均优于对照组(P<0.01)。结论:高通量透析模式可以有效改善尿毒症患者顽固性高血压。

Objective： To investigate the influence of high-flux dialysis（ HFD） on resistant hypertension in patients with uremia.Methods： Thirty cases with resistant hypertension in uremia patients were randomly assigned to observation group and control group.Low flux dialyzers were used in control group and high flux dialyzers were used in observation group. The dialysis time was 12 hours every week and the observation duration was 12 weeks. The changes of systolic blood pressure,diastolic blood pressure and mean arterial pressure in the two groups before and after treatment were observed. Results： The decrease degrees of systolic blood pressure,diastolic blood pressure and mean arterial pressure in observation group were superior than in control group after 12 weeks,which had statistical significances（ P〈0. 01）. Conclusions： HFD mode can effectively improve resistant hypertension in uremia patients.