期刊文献+

孤独症谱系障碍脑结构和功能异常研究进展 被引量:2

原文传递
导出
摘要 孤独症谱系障碍(autism spectrum disorders,ASD)是一类神经发育性障碍,主要特征是社会交往缺陷和兴趣行为刻板,大多需终生看护,疾病负担巨大。从首次报道至今70余年来,发病率迅猛攀升,而病因和发病机制尚未阐明。 既往研究提示,可能存在的遗传因素和影响胎婴儿神经系统发育的某些因素,使用功能影像学技术进一步揭示ASD存在脑结构和功能异常的某些特征,这些特征有望成为ASD早期诊断的生物学标志,因此成为目前热点研究领域。本文综述了ASD脑结构和功能异常的主要研究进展,为今后该领域研究探索可行的方向。
作者 赵雅芬 金宇
出处 《中国实用儿科杂志》 CSCD 北大核心 2014年第10期790-793,共4页 Chinese Journal of Practical Pediatrics
基金 国家自然科学基金(41030053) 广东省科技计划项目(2011B031800020) 广东省大学生创新训练项目[中大教务(2013)38号文(1055813209)] 中山大学实验室开放基金[中大设备(2013)6号 No.KF201310]
关键词 孤独症谱系障碍 神经影像学 磁共振 计算机断层扫描 autism spectrum disorders neuroimaging study magnetic resonance imaging CT
  • 相关文献

参考文献30

  • 1Kent RG,Carrington SJ,Le Couteur A,et al.Diagnosing autism spectrum disorder:who will get a DSM-5 diagnosis?[J].J Child Psychol Psychiatry,2013,54(11):1242-1250.
  • 2Carper RA,Courchesne E.Localized enlargement of the frontal cortex in early autism[J].Biol Psychiatry,2005,57(2):126-133.
  • 3Knaus TA,Tager-Flusberg H,Mock J,et al.Prefrontal and occipital asymmetry and volume in boys with autism spectrum disorder[J].Cogn Behav Neurol,2012,25(4):186-194.
  • 4Mori K,Toda Y,Ito H,et al.A proton magnetic resonance spectroscopic study in autism spectrum disorders:amygdala and orbito-frontal cortex[J].Brain Dev,2013,35(2):139-145.
  • 5Bastiaansen JA,Thioux M,Nanetti L,et al.Age-related increase in inferior frontal gyrus activity and social functioning in autism spectrum disorder[J].Biol Psychiatry,2011,69(9):832-838.
  • 6Ulay HT,Ertugrul A.Neuroimaging findings in autism:a brief review][J].Turk Psikiyatri Derg,2009,20(2):164-174.
  • 7Saitovitch A,Bargiacchi A,Chabane N,et al.Social cognition and the superior temporal sulcus: implications in autism[J].Rev Neurol (Paris),2012,168(10):762-770.
  • 8Eyler LT,Pierce K,Courchesne E.A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism[J].Brain,2012,135(Pt3):949-960.
  • 9Saitovitch A,Bargiacchi A,Chabane N,et al.Social cognition and the superior temporal sulcus: implications in autism[J].Rev Neurol (Paris),2012,168(10):762-770.
  • 10Redcay E. The superior temporal sulcus performs a common function for social and speech perception: implications for the emergence of autism[J].Neurosci Biobehav Rev,2008,32(1):123-142.

同被引文献44

  • 1李建华,钟建民,蔡兰云,陈勇,周末芝.儿童期孤独症评估量表的临床应用研究[J].中国儿童保健杂志,2005,13(3):267-268. 被引量:24
  • 2苗硕,杨健.注意缺陷多动障碍患儿认知功能检测技术研究进展[J].国际儿科学杂志,2015,42(6):673-677.
  • 3Leitner Y. The co-occurrence of autism and attention deficit hyperactivity disorder in children - what do we know? [ J]. Front Hum Neurosci ,2014,8:268.
  • 4Chamsil C, Sriapai P. Attention deficit hyperactivity symptoms in children with autistic disorder: a cross-sectional descriptive study [ J ]. J Med Assoc Thai, 2011,94 ( 2 ) : 231-234.
  • 5Ronald A, Simonoff E, Kuntsi J, et al. Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample [J]. J Child Psychol Psychiatry, 2008,49 ( 5 ) : 535-542.
  • 6Ogino T, Hattori J, Abiru K, et al. Symptoms related to ADHD observed in patients with pervasive developmental disorder[J]. Brain Dev,2005,27 ( 5 ) : 345-348.
  • 7Icasiano F, Hewson P, Machet P, et al. Childhood autism spectrum disorder in the Barwon region: a community based study [ J ]. J Paediatr Child Health, 2004,40 (12) :696-701.
  • 8Sinzig J, Bruning N, Morsch D, et al. Attention profiles in autistic children with and without comorbid hyperactivity and attention problems[J].Acta Neuropsychiatr, 2008,20 (4) : 207-215.
  • 9Ames CS, White SJ. Are ADHD traits dissociable from the autistic profile? Links between cognition and behaviour [ J ]. J Autism Dev Disord,2011,41 ( 3 ) :357-363.
  • 10Taurines R, Schwenck C, Westerwald E, et al. ADHD and autism: differential diagnosis or overlapping traits? A selective review[ J]. Atten Defic Hyperact Disord ,2012,4 ( 3 ) : 115-139.

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部