期刊文献+

右美托咪定在支撑喉镜下会厌囊肿切除术中的应用

下载PDF
导出
摘要 目的:探讨右美托咪定辅助全身麻醉在支撑喉镜下会厌囊肿切除术中的效果及安全性。方法:选取60例行支撑喉镜下会厌囊肿切除术患者,随机分为对照组(n=30)与观察组(n=30);2组患者均行气管插管全身静脉麻醉,观察组患者麻醉诱导前10分钟静脉推注负荷剂量(0.5μg/kg)右美托咪定,而对照组患者麻醉诱导前10分钟静脉推注等量生理盐水;观察并记录2组患者的MAP值和HR值,丙泊酚、舒芬太尼等麻醉药的使用量,自主呼吸恢复时间、拔管时间,并观察患者术后咽痛、呛咳、苏醒躁动等不良反应的发生情况。结果:与对照组相比,观察组患者具有比较好的血流动力学稳定性( P<0.05);观察组患者丙泊酚、瑞芬太尼等麻醉药物用量均明显少于对照组(P<0.05);观察组患者呛咳及苏醒期躁动发生率均明显低于对照组(P<0.05)。结论:术前泵注负荷剂量右美托咪辅助全身麻醉用于支撑喉镜下会厌囊肿切除术,能够维持患者在麻醉操作和手术时的血流动力学相对稳定,同时减少不良反应的发生,是一种安全有效的麻醉方法。
作者 刘志成 韩靓
出处 《中国伤残医学》 2014年第21期69-70,共2页 Chinese Journal of Trauma and Disability Medicine
  • 相关文献

参考文献9

  • 1Mantz J, Josserand J, Hamada S. Dexmedetomidine : newlnsights. Eur J Anaesthesiol,2011,28 :3 - 6.
  • 2Dasta JF, Kan - Gill SL, Peneina M, et al. A cost - mini - mization analysis of dexmedetomidine compared with midazolam for long N term sedation in the intensive care unit [ J]. Crit Care Med ,2010, 38 (2) :497 -503.
  • 3Wijeysundera DN, Naik iS, Beattie WS. Alpha - 2 adrenergie ago- nists to prevent perioperative cardiovascular complications : a meta- analysis [J]. Am J Med, 2003,114(9) : 742 -752.
  • 4Sulaiman S, Karthekeyan RB, Vakanmdi M, et al. The effects of dexmedetomidine on attenuation of stress response to endotraeheal intubation in patients undergoing elective off - pump coronary artery bypass grafting [J-. Ann Card Anaesth, 2012, 15(1) :39 -43.
  • 5Keniya VM, Ladi S, Naphade R. Dexmedetomidine attenuates sympathoadrenal 34 response to tracheal intubation and reduces porioperative anaesthetic requirement. Indian J Anaesth [ J ]. 2011,55(4) :352 -357.
  • 6Lou YP, Franco - Cereceda A, Lundberg JM. Variable alpha 2 adrenoeeptor - mediated inhibition of bronchoconstriction and pep- tide release upon activation of pulmonary afferents [ J]. Eur J Phar- maeol, 1992, 210(2) :173 - 181.
  • 7Lin TF, Yeh YC, Lin FS, et al. Effect of combining dexmedetomi- dine and morpliine for intravenous patient - controlled analgesia [ J]. Br J Anaestli, 2009, 102( 1 ) : 117 - 122.
  • 8Khan ZP, Fergnson CN, Jones RM. Alpha - 2 and imidazoline re- ceptor agoniststlieir pliannacology and tlierapentic role[ J]. Anaest- liesia 1999,54(2) :146 - 165.
  • 9KOROGLU A, TEKSAN H, SACIR O, et al. A comparison of the sedative, hemedynamie, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonanee imaging [J]. Anesth Analg, 2006, 103(1) :63 -67.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部