期刊文献+

原发性肝癌经导管肝功脉化疗栓塞治疗的进展 被引量:8

下载PDF
导出
摘要 原发性肝癌在世界范围内发病率居第6位,病死率居第3位[1],目前手术切除仍是常用治疗方法,然而能实施外科切除者不足20%[2],不能切除者的自然生存期仅3~6个月,经导管肝功脉化疗栓塞(transcatheter arterial chemoembolization , TACE)是目前公认的首选非手术技术方法。但TACE技术存在肿瘤坏死不完全、需多次治疗等缺陷;同时其对播散卫星灶和门静脉癌栓的治疗效果欠佳,且难于控制病灶的远处转移,这些都成为限制T ACE进一步发展的障碍。近年来随着技术的改进及新栓塞材料的应用,TACE治疗原发性肝癌在抑制肿瘤生长及提高患者生存率方面明显改善,现就 T ACE的进展进行综述。
作者 青云 罗小平
出处 《重庆医学》 CAS CSCD 北大核心 2014年第29期3970-3973,共4页 Chongqing medicine
  • 相关文献

参考文献4

二级参考文献26

共引文献51

同被引文献90

  • 1李哲夫,李杨,陈孝平.原发性肝癌的诊治进展及展望[J].临床普外科电子杂志,2013,1(2):11-13. 被引量:5
  • 2Chang CH, Chau GY, Lui WY, Tsay SH, King KL, Wu CW. Long-term results of hepatic resection for hepatocellular carcinoma originating from the noncirrhotic liver. Arch Surg 2004; 139: 320-325; discussion 326.
  • 3Tung-Ping Poon R, Fan ST, Wong J. Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. Ann Surg 2000; 232: 10-24.
  • 4Martin J, Bhanot K, Athreya S. Complications and reinterventions in uterine artery embolization for symptomatic uterine fibroids: a literature review and meta analysis. Cardiovasc Intervent Radiol 2013; 36: 395-402.
  • 5Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, Greninger P, Thompson IR, Luo X, Soares J, Liu Q, Iorio F, Surdez D, Chen L, Milano RJ, Bignell GR, Tam AT, Davies H, Stevenson JA, Barthorpe S, Lutz SR, Kogera F, Lawrence K, McLaren-Douglas A, Mitropoulos X, Mironenko T, Thi H, Richardson L, Zhou W, Jewitt F, Zhang T, O'Brien P, Boisvert JL, Price S, Hur W, Yang W, Deng X, Butler A, Choi HG, Chang JW, Baselga J, Stamenkovic I, Engelman JA, Sharma SV, Delattre O, Saez-Rodriguez J, Gray NS, Settleman J, Futreal PA, Haber DA, Stratton MR, Ramaswamy S, McDermott U, Benes CH. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 2012; 483: 570-575.
  • 6Ryu JS, Hong YC, Han HS, Lee JE, Kim S, Park YM, Kim YC, Hwang TS. Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy. Lung Cancer 2004; 44: 311-316.
  • 7Jakobsen A, Nielsen JN, Gyldenkerne N, Lindeberg J. Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity. J Clin Oncol 2005; 23: 1365-1369.
  • 8Derwinger K, Wettergren Y, Odin E, Carlsson G, Gustavsson B. A study of the MTHFR gene polymorphism C677T in colorectal cancer. Clin Colorectal Cancer 2009; 8: 43-48.
  • 9Marcuello E, Altés A, del Rio E, César A, Menoyo A, Baiget M. Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients. Int J Cancer 2004; 112: 733-737.
  • 10Villafranca E, Okruzhnov Y, Dominguez MA, García-Foncillas J, Azinovic I, Martínez E, Illarramendi JJ, Arias F, Martínez Monge R, Salgado E, Angeletti S, Brugarolas A. Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J Clin Oncol 2001; 19: 1779-1786.

引证文献8

二级引证文献57

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部