辨证论治慢性胃炎随机平行对照研究

Type Differentiation and Treatment of Chronic Gastritis Random Parallel Control Study

[目的]观察辨证论治慢性胃炎疗效。[方法]使用随机平行对照方法,将80例门诊及住院患者按抽签法简单随机分为两组。对照组40例奥美拉唑,40mg/次,1次/d。甲硝唑,0.2g/次,3次/d。治疗组40例,脾胃虚寒,温中祛寒(党参25g,白芍20g,砂仁、甘草各15g,茯苓、白术、桂枝各10g);胃阴亏虚,滋阴补胃,和中止痛(生地黄、北沙参各20g,白芍、麦冬、当归、枸杞子、石斛各15g,川楝子10g,甘草5g);肝胃郁热,疏肝解郁,泄热和胃(生大黄、黄芪、吴茱萸、白芍、金钱草各15g,柴胡、黄连、栀子炒、枳实各10g);瘀阻胃络,活血化疲(丹参、蒲公英各30g,白花蛇舌草、半枝莲各20g,元胡、香附各12g,川楝子、五灵脂、蒲黄、莪术、三棱、乌药各10g,砂仁6g);肝胃气滞,疏肝泄热,调气和胃(柴胡、白芍各15g,香附、茯苓、白术、元胡醋各12g,川楝子、当归、吴茱萸、苏梗、乌药、枳壳、佛手各10g,黄连、甘草各6g);均1剂/d,水煎200mL,早晚饭后温服。连续治疗6周为1疗程。观测临床症状、胃黏膜状况、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈18例,显效14例,有效6例,无效2例,总有效率95.00%。对照组痊愈10例,显效8例,有效9例,无效13例,总有效率67.50%。治疗组疗效优于对照组(P<0.05)。[结论]辨证论治慢性胃炎疗效显著,值得推广。

[ Objective ] To observe the curative effect for the treatment of chronic gastritis. [ Methods ] Using random parallel control method, 80 cases of outpatient and inpatient is divided into two groups according to random number table method. The control group, 40 cases of omeprazole 40 mg/times, 1/d. Metronidazole, 0.2 g/time, 3 times/d. Treatment group （ 40 cases of spleen and stomach cold： treatment to remove cold in temperature （Dangshen25g, Baishao 20 g, Sharen, Gancaoeach 15g, Fuling, Baizhu, Guizhi lOg）; Stomach Yin deficiency, treatment to nourish Yin to fill the stomach, and the pain （ Shengdihaung, Beishasheneach20g, Baishao, Maidong, Danggui, Gouqizi, Shihueach 15g, Chuanjizil0g, GancaoSg） . Liver stomach wind-cold, Shengdahuang, Huangqi, Wuzhuyu, Baishao, Jinqiancao each 15g, Chaihu, Huanglian, Chaozhizi, Zhishil0g ） ; Gastric stasis resistance winding： treatment to invigorate the circulation of the exhausted （ Danshen, Pugongying each 30g, Baihuasheshecao, Banzhilian each 20g, Yuanhu, Xiangfu 12g, Chuanjizi, Wulingzhi, Puhuang, E＇ zhu, Sanleng, Wuyao each 10 g, Sharen6g） ;Liver stomach and qi stagnation：treatment for liver heat release, the gas and stomach （ Chaihu, Baishao each 15g, Xiangfu, Fuling, Baizhu, Cuyuanhueach 12g, Chuanjiezi, Danggui, Wuzhuyu, Sugeng, Wuyao, Zhike, Foshou each 10g, Huanglian, Gancao each 6 g ） ;All agent l/d, Fried 200 ml water, morning and evening after dinner warm clothing. For treatment of 6 weeks for 1 course of treatment.Observation of clinical symptoms and adverse reactions. As a course treatment, judge curative effect. [ Results ] The treatment group （ 18 cases cured, 14 cases were markedly effective, 6 cases effective, ineffective in 2 cases, total effective rate was 95.00%. The control group, 10 cases were cured, 8 cases were markedly effective, effective 9 cases, 13 cases of invalid, total effective rate was 67.50%. The treatment group curative effect is better than that of control group （ P〈0.05 ） . [ Conclusion ] The treatment of chronic gastritis, is worth promoting.