血栓通联合依达拉奉与基础治疗治疗急性脑梗死随机平行对照研究

Xueshuantong Combined with Edaravone in Treatment of Acute Cerebral Infarction Randomized Parallel Controlled Study

[目的]观察血栓通联合依达拉奉与基础治疗急性脑梗死疗效。[方法]使用随机平行对照方法,将60例住院患者按就诊顺序编号法简单随机分为两组。对照组30例脱水、降压、营养脑细胞、预防电解质紊乱等对症支持治疗;依达拉奉30mg+5%葡萄糖250mL,1次/d,静滴。治疗组30例血栓通5mL+5%葡萄糖250mL中静滴;依达拉奉与基础治疗同对照组。连续治疗7d为1疗程。观测临床症状、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组基本治愈16例,显著进步9例,进步2例,无效3例,总有效率90.00%。对照组基本治愈12例,显著进步3例,进步6例,无效9例,总有效率70.00%。治疗组疗效优于对照组(P<0.05)。神经功能缺损评分改善治疗组治疗组优于对照组(P<0.01)。[结论]血栓通联合依达拉奉与基础治疗急性脑梗死疗效显著,值得推广。

[ Objective ] Xueshuantong combined with edaravone in treatment of acute cerebral infarction. [ Method ] Using randomized controlled methods, 60 cases of hospitalized patients according to the order number method and were randomly divided into two groups. A control group of 30 cases of dehydration, buck, nourishing brain cells, prevention of electrolyte disorders such as symptomatic and supportive treatment. Edaravone 30mg＋5% glucose solution 250mL, 1 /d, intravenous drip. The treatment group of 30 eases of Xueshuantong 5mL＋5% glucose solution / 250mL normal saline intravenously; western medicine treatment with the control group. Continuous treatment with 7d for 1 courses. Observation of clinical symptoms, adverse reaction. Continuous 2 courses of treatment, the curative effect. [ Results ] the treatment group 16 cases were cured, 9 cases of significant progress, progress in 2 cases, 3 cases ineffective, the total efficiency of 90%. The control group cured 12 cases, 3 cases of significant progress, progress in 6 cases, 9 cases ineffective, the total efficiency of 70%. The treatment group was better than control group （P〈0.05） . Improvement of neurological function deficit scores of treatment group, the treatment group than the control group （ P〈 0.01 ） . [ Conclusion ] Xueshuantong combined with edaravone in treatment of acute cerebral infarction effect is significant, worthy of promotion.