基于使用的网状Meta分析软件的比较研究与选择

Software for Network Meta-Analysis: A Usage-based Comparative Study

目的比较各种网状Meta分析(NMA)软件的特征及功能,为使用者选择软件提供参考。方法计算机检索PubMed、CNKI、Stata公司官方网站、R软件官方网站和Google,收集具有NMA功能的软件及程序包,检索时限截至2014年7月。下载软件和程序包及其使用指南,用示例进行计算。对软件的基本特征、功能和计算结果进行比较分析。结果共纳入11款软件,包括编程软件和非编程软件,主要基于贝叶斯学派和频率学派研发。大多数软件已具操作简单、易掌握、计算准确及图形绘制优良等优点,但无一款同时具备较佳计算能力与绘图功能的软件,必需多款软件联合来实现。结论建议使用者首先依据自身编程基础与习惯等选取,可考虑选用两种或三种软件相互配合来实现NMA。建议研发一款功能完备、操作简单的免费软件。

Objective To compare the characteristics and functions of the network meta-analysis software and for providing references for users. Methods PubMed, CNKI, official website of Stata and R, and Google were searched to col- lect the software and packages that can perform network meta-analysis up to July 2014. After downloading the software, packages, and their user guides, we used the software and packages to calculate a typical example. The characteristics, func- tions, and computed results were compared and analyzed. Results Finally, 11 types of software were included, including programming and non-programming software. They were developed mainly based on Bayesian or Frequentist. Most types of software have the characteristics of easy to operate, easy to master, exactitude calculation, or good graphing; however, there is no software that has the exactitude calculation and good graphing at the same time, which needs two or more kinds of soft- ware combined to achieve. Conclusion We suggest the user to choose the software at least according to personal program- ruing basis and custom; and the user can consider to choose two or more kinds of software combined to finish the ob）ective network meta-analysis. We also suggest to develop a kind of software which is characterized of fully function, easy operation, and free.