摘要
黑色素瘤是恶性程度最高的皮肤肿瘤,基于对黑色素瘤细胞的基因突变和免疫系统研究的深入,分子靶向和免疫治疗药物为晚期黑色素瘤带来了新的契机。全文总结近年治疗恶性黑色素瘤靶向药物及相关治疗通路的研究进展。
Melanoma is the most aggressive tumor in skin malignancies. The molecular target and immune agents have brought new therapy opportunity for advanced melanoma,which is based on intensive studies on gene mutations of melanoma cells and immune system. The research progress of targeted agents and related treatment pathway for malignant melanoma treatment was summarized in this paper.
出处
《中国肿瘤》
CAS
2014年第10期854-859,共6页
China Cancer
关键词
恶性黑色素瘤
分子靶向治疗
免疫治疗
malignant melanoma
molecular targeted therapy
immunotherapy