螺杆菌感染与慢性肝病研究现状与进展

Current status and progress in research on helicobacter infection and chronic liver diseases

有关螺杆菌感染与肝病相关的研究逐渐增加,主要是研究螺杆菌对肝病的影响,而肝病对螺杆菌的作用研究甚少。介绍了肝病时螺杆菌的细菌学、流行率,螺杆菌引起肝病的发病机制和诊断。至目前为止现已得到共识与人类肝病相关的螺杆菌有3种,即H.pylori、H.heilmanni和H.cinaedi,其中主要是H.pylori的研究,对于后两者研究不多,而肝螺杆菌属于H.pylori的1个新型。研究显示今后应主要在发病机制和预防上做更深入的研究。

There has been increasing research on the association between Helicobacter infection and liver diseases,mostly the influence of Helicobacter on liver diseases. The prevalence and bacteriology of Helicobacter during the development of liver diseases,the mechanism by which Helicobacter causes liver diseases,and the diagnosis of liver diseases are reviewed. So far consensus has been reached that three species of Helicobacter are associated with human liver diseases,namely H. pylori,H. heilmanni,and H. cinaedi. H. pylori has been studied most extensively,but there is little research on the latter two. H. hepaticus is a new type of H. pylori. Studies have shown that further research should be conducted on the pathogenesis and prevention of chronic liver diseases.