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下咽和食管异时性重复癌 被引量:2

Metachronous hypopharyngeal and esophageal multiple primary carcinomas
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摘要 重复癌是指同一宿主在同一器官或成对器官、同一系统不同部位以及不同器官同时或先后发生>2个的原发恶性肿瘤。本文报道1例下咽和食管异时性重复癌,其中下咽癌发现于食管癌术后内镜复查阶段,临床分期处于T1N0M0。已有学者建议可应用内镜下黏膜剥离术治疗早期下咽癌,有望获得良好治疗效果。因此,该重复癌病例提示内镜医生在常规胃镜检查时除仔细观察食管、胃以及十二指肠部位病变外,还应注意咽喉部特别是梨状隐窝等罕见部位的可疑早期癌变,并且可以应用新型内镜技术提高早期下咽癌的检出率,延长患者的生存期。 Multiple primary carcinomas refer to two or more primary malignancies synchronously or metachronously occur in the same organ,different locations of one system or different organs in one person. One case of metachronous hypopharyngeal and esophageal multiple primary carcinomas was reported. Hypopharyngeal carcinoma was diagnosed during routine gastroscopy examine after esophageal carcinoma surgery and clinical stage was T1N0M0. Some scholars suggest endoscopic submucosal dissection for early stage hypopharyngeal carcinoma. Endoscopists should pay attention to suspicious lesions in pharynx besides esophagus,stomach and duodenum,and new techniques can be applied for the detection of early stage hypopharyngeal carcinomas.
出处 《实用肿瘤杂志》 CAS 2014年第5期460-462,共3页 Journal of Practical Oncology
基金 国家公益卫生行业专项基金(200802112) 国家自然基金一般项目(81372302) 浙江省自然基金(Y2080001 Y12H160121) 浙江省科技厅重大科技专项(2009C03012-5 2013C03044-5) 浙江省卫生厅一般项目(201343550) 浙江省教育厅一般项目(Y201328489)
关键词 食管肿瘤/外科学 下咽肿瘤/外科学 肿瘤 多原发性 内窥镜检查 esophageal neoplasms/surgery hypopharyngeal neoplasms/surgery neoplasms multiple primary endoscopy
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参考文献5

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同被引文献13

  • 1李晓明,邸斌,邵永良,成继民,马宏敏,高春梅,尚耀东.下咽癌颈淋巴结转移的临床病理学特点及其对预后的影响[J].中华耳鼻咽喉科杂志,2004,39(12):741-745. 被引量:21
  • 2赵龙珠,穆晓峰,刘宏斌,等.下咽癌同期合并食管癌的重复癌3例.中华高血压杂志,2015,23(2):457.457.
  • 3Morris LG, Sikora AG, Patel SG, et al. Second primary cancers after an index head and neck cancer: subsite-specific trends in the era of human papillomavirus-associated oropharyngeal cancer. J Clin Oncol, 2011, 29(6): 739-746.
  • 4Morris LGT, Sikora AG, Hayes RB, et al. Anatomic sites at elevated risk of second primary cancer after an index head and neck cancer. Cancer Causes & Control, 2011, 22(5): 671-679.
  • 5Chu PY, Li WY, Chang SY, et al. Clinical and pathologic predictors of survival in patients with squamous cell carcinoma of the hypop- harynx after surgical treatment. Ann Otol Rhinol Laryngol, 2008, 117(3): 201-206.
  • 6Guermazi A, Brice P, Henneqiun C, et al. Lymphography: an old technique retains its usefulness. Radiographics, 2003, 23(6): 1541- 1558.
  • 7Kato Y, Tsuyuki A, Kikuchi K, et al. Primary jejunal adenocarcinoma as part of multiple primary cancers of the digestive tract. J Gastroen- terol Hepatol, 2008, 23(4): 673-677.
  • 8Wen D, Wang S, Zhang L, et al. Early onset, multiple primary malig- nancies, and poor prognosis are indicative of an inherited predisposi tion to esophageal squamous cell carcinoma for the familial as oppo- sed to the sporadic casesan update on over 14-year survival. Eur J Med Genet, 2009, 52(6): 381-385.
  • 9张才云,陈世彩,郑宏良,李志刚,朱敏辉,刘菲.同时发生的下咽-胸段食管多原发癌的外科治疗(附7例报告)[J].第二军医大学学报,2010,31(9):998-1001. 被引量:4
  • 10曹轶佚,周梁,吴海涛,李筱明,黄维庭,陈小玲,李采,陶磊.下咽癌386例临床特征及疗效分析[J].中华耳鼻咽喉头颈外科杂志,2016,51(6):433-439. 被引量:34

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