糖尿病患者眼肌麻痹的治疗分析

The clinical analysis of diabetes-associated ophthalmoplegia

目的探讨糖尿病患者眼肌麻痹的临床特点、发病机制及治疗。方法收集2008年6月至2013年6月在青岛市市立医院眼科就诊的65例Ⅱ型糖尿病患者并发眼肌麻痹的临床资料进行分析。结果在65例患者中，有61例以复视就诊，4例以上睑下垂就诊，瞳孔均未受累。经治疗并随诊半年，42例治愈，治愈时间为55～97天；好转17例；6例无明显改善。结论该病起病急，动眼神经受累最常见，外展神经次之，多表现为复视及上睑下垂等症状，瞳孔一般不受累。早期诊断，及时治疗，大多数可获得良好疗效。

Objective To explore clinical features and pathogenesis of diabetes-associated oph- thalmoplegia. Methods Sixty-five cases which were admitted ophthalmoplegia with type 2 diabetes from June 2008 to June 2013 in our hospital were retrospectively analyzed. Results Among 65 cases, monocular involvement with ptosis of the upper eyelid occurred in 4 cases, 61 suffered from diplopia without pupillary abnormality, 42 were healed. The treatment time was from 55 to 97 days; 17 cases were better and 6 cases had no change. Conclusions Diabetes-associated ophthalmoplegia is mostly in acute condition. Oculomotor nerve damage is the most common cause of the disease. It is well effective to active treat the primary affection of diabetes and the complication of the nerve.