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机械应力对脂肪组织中细胞的影响的研究进展

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摘要 自1957年Neumann报道软组织扩张器以来,通过不断的改进和推广,软组织扩张术已成为整形外科的常规治疗手段之一.皮肤软组织扩张器是通过间断地向扩张囊内注射液体以增加扩张器容量,使其对表面皮肤软组织产生压力.体外负压吸引装置通过应用来自外部的负压扩张皮肤和软组织,即通过持续、低水平的负压产生一个向外的牵张力来刺激乳房组织的增生,以达到隆乳的目的,它的主要优势是外部装置,排除了外科手术[1].一个压力装置产生的力通过各种机械应力作用,包括剪切力、拉伸、紧张、牵引和压缩,传递到细胞和亚细胞结构,通过一系列传导路径转变成生物信号[2].目前已经证实应用的机械应力能影响组织生长、细胞功能和甚至存活[3].
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2014年第10期2364-2365,共2页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助项目(81071589)
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二级参考文献36

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