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获得性凝血因子ⅩⅢ缺乏症致牙龈出血的临床分析 被引量：3

Clinical analysis of gum bleeding caused by acquired factor ⅩⅢ deficiency disease
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摘要 获得性凝血因子ⅩⅢ缺乏症极罕见,笔者在临床工作中发现1例以牙龈出血为首发症状的获得性凝血因子ⅩⅢ缺乏症。对此症进行分析,并对相关文献进行了复习。 Acquired factor XIII deficiency disease is rare.One case with gum bleeding as the first symptom caused by acquired factor XIII de-ficiency disease was encountered.The case was analyzed and relevant literatures were reviewed.
作者 谭葆春 肖健平
机构地区 南京大学口腔医学院·南京市口腔医院
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 2014年第5期715-718,共4页 Journal of Practical Stomatology
基金 国家自然科学基金(编号:81271155) 南京市医学科技发展专项资金(编号:ZKX13050) 江苏省临床医学科技专项重点病种的规范化诊疗研究(编号:BL2013002)
关键词 获得性凝血因子XIII缺乏症 牙龈出血 Acquired factor XIII deficiency disease Gum bleeding
分类号 R781 [医药卫生—口腔医学]
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参考文献11

  • 1Boehlen F, Casini A, Chizzolini C, et al. Acquired factor XIII deficiency: A therapeutic challenge[ J]. Thromb Haem- ost, 2013, 109(3) : 479 -487.
  • 2Wiegering V, Andres O, Sehlegel PG, et al. Hyperfibrinolys- is and acquired factor XIII deficiency in newly diagnosed pe- diatric malignancies[J]. Haematologica, 2013, 98(8): e90 -91.
  • 3Kessel R, Hu C, Shore-Lesserson L, et al. A child with ac- quired factor XIII deficiency: Case report and literature re- view[J]. Haemophilia, 2013, 19(6) : 814 -826.
  • 4Kawano H, Yamamoto D, Uchihashi Y, et al. Severe inhibi- tor-negative acquired factor XIII/13 deficiency with aggres- sive subdural haemorrhage [ J ]. Blood Coagul Fibrinolysis, 2013, 24(6) : 638 -641.
  • 5Lim W, Moffat K, Hayward CP. Prophlactic and periopera- tive replacement therapy for acquired factor XIII deficiency [J]. J Thmmb Haemost, 2004, 2(6) : 1017 -1019.
  • 6Lorand L, Velasco PT, Hill JM, et al. Intracranial hemor- rhage in systemic lupus erythematosus associated with an au- toantibody against actor XIII[ J]. Thromb Haemost, 2002, 88 (6) : 919 -923.
  • 7Ajzner E,Schlammadinger A, Ker6nyi A, et al. Severe bleed-ing complications caused by an autoantibody against the B subunit of plasma factor XIII : A novel form of acquired factor XIII deficiency [ J ]. Blood,2009,113 ( 3 ) :723 - 725.
  • 8Luo Y, Zhang G, Zuo W, et al. Acquired factor XIII inhibi- tor in monoclonal gammopathy of undetermined significance: Characterization and cross-linked fibrin ultrastructure [ J ]. Ann Hematol, 2010, 89(8) : 833 -834.
  • 9Gregory TF, Cooper B. Case report of an acquired factor XIIIinhibitor: Lagnosis and management [ J ]. Proc ( Bayl Univ Med Cent), 2006, 19(3) : 221 -223.
  • 10Lira W, Moffat K, Hayward CP. Prophlactic and periopera- tive replacement therapy for acquired factor XIII deficiency [J]. J Thmmb Haemost, 2004, 2(6) :1017 -1019.

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实用口腔医学杂志
2014年 第5期

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