镁与骨质疏松

Magnesium and osteoporosis Magnesium and osteoporosis

镁离子是人体内重要的阳离子,参与多种生理活动。。镁缺乏易导致骨质疏松,适当补充镁可以增强骨密度,改善骨组织形态,缓解骨质疏松等症状。此外,可降解金属镁及其镁合金因其在骨折和骨缺损治疗中的潜在优势,有望在未来的骨外科治疗中得到广泛应用。然而镁离子促进成骨细胞增殖和分化,促进骨骼生长作用机制仍待深入研究。本文综述了镁在骨代谢中的作用及相关分子机制的最新研究进展。

Magnesium is the major intracellular divalent cation and is involved in many physiological processes.Magnesium deficiency may lead to osteoporosis.However, magnesium supplementation may promote bone growth and prevent osteoporosis. This paper reviews the progress on the mechanism of magnesium-stimulated bone growth and bone metabolism.