期刊文献+

肾上腺脑白质营养不良一例

下载PDF
导出
摘要 患者男性,15岁,主因双眼视物不清、记忆力减退进行性加重2年,于2012年6月18日入院.患者2年前出现双眼视物不清,认为是因患者喜玩电脑游戏而出现近视,予佩戴约-300度眼镜,但视力仍下降,换为-400多度的眼镜仍视物不清,并相继出现记忆力、计算力减退,学习成绩下降,由原来的班内前十名变为倒数几名,以上两组症状呈进行性加重.6个月前逐渐表现反应迟钝,行走不稳,尤其爬坡时明显,不能上体育课,容易疲劳.于入院前1个月辍学,但生活尚可自理,患者自发病以来精神稍差,食欲不佳,进食量小,无明显头痛、头晕,无恶心、呕吐,无听力异常,无吞咽困难、饮水呛咳、肢体无力麻木、无大小便障碍及意识障碍.
出处 《脑与神经疾病杂志》 2014年第5期381-383,共3页 Journal of Brain and Nervous Diseases
  • 相关文献

参考文献11

  • 1Moser HW.Adrenoleukodystrophy:phenotype,genetics,pathogenesis and therapy.Brain,1997,120:1485-1508.
  • 2Moser HW,Raymond GV,Dubey P.Adrenoleukodystrophy:new approaches to a neurodegenerative disease.JAMA,2005,294:3131-3134.
  • 3Loes DJ,Fatemi A,Melhem ER,et al.Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy.Neurology,2003,61:369-374.
  • 4Engelen M,Kemp S,de Visser M,et al.X-linked adrenoleukodystrophy (X-ALD):clinical presentation and guidelines for diagnosis,follow-up and management.Orphanet J Rare Dis,2012,7:51.
  • 5Kim JH,Kim HJ.Childhood X-linked adrenoleukodystrophy:clinical-pathologic overview and MR imaging manifestations at initial evaluation and follow-up.Radiographics,2005,25:619-631.
  • 6Melhem ER,Loes DJ,Georgades CS,et al.X-linked adrenoleukodystrophy:the role of contrast-enhanced MR imaging in predicting disease progression.AJNR Am J Neuroradiol,2000,21:839-844.
  • 7Eichler F,Mahmood A,Loes D,et al.Magnetic resonance imaging detection of lesion progression in adult patients with X-linked adrenoleukodystrophy.Arch Neurol,2007,64:659-664.
  • 8Seshadri S,Beiser A,Selhub J,et al.Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.N End J Med,2002,7:476-483.
  • 9Moser HW,Raymond GV,Lu SE,et al.Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil.Arch Neurol,2005,62:1073-1080.
  • 10Mahmood A,Raymond GV,Dubey P,et al.Suvival analysis of haematopoietic cell transplantation for childhood cerebral X-linked adrenoleukodystrophy:acomparison study.Lancet Neurol,2007,6:687-692.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部