2012-2013年我院抗肿瘤类中药注射剂应用分析

Application of Anticancer Traditional Chinese Medicine Injection in Our Hospital between 2012 and 2013

目的分析我院2012～2013年抗肿瘤类中药注射剂的应用情况,为临床合理用药提供参考。方法采用回顾性调查的方法对我院2012～2013年抗肿瘤类中药注射剂的品种、抗肿瘤类中药注射剂用药总金额在中药注射剂用药总金额中的构成比、单品种抗肿瘤类中药注射剂用药金额在抗肿瘤类中药注射剂用药总金额中的构成比、用药频度（DDDs）、日用药金额（DDC）及药物不良反应发生率进行统计分析。结果 2012～2013年,我院共有4种抗肿瘤类中药注射剂,其用药总金额与构成比变化均不明显;康艾注射液的用药金额、构成比、DDDs均连续两年位居第一,且呈较大幅度上升,2013年的构成比达到85.09%;艾迪注射液的的用药金额、构成比、DDDs下降幅度较大;4个品种的DDC均无显著变化;抗肿瘤类中药注射剂不良反应发生率较低。结论康艾注射液在抗肿瘤类中药注射剂中占主导地位,但用药结构不合理,需要进一步加强管理与监督。

Objective To analyze the application of anticancer traditional Chinese medicine（TCM） injection in our hospital from 2012 to 2013,and provide references for the rational clinical use of drug.Methods The drug varieties,constituents ratio of total consumption of anticancer TCM injection in TCM injection,constituents ratio of total consumption of single varieties in anticancer TCM injection,DDDs,daily drug cost（DDC） and incidence of adverse drug reactions were analyzed with retrospective survey methodology.Results There were four varieties of anticancer TCM injection in our hospital.Their total consumption sum and constituents ratios all had little changes.The consumption sum,constituents ratio,DDDs of Kang＇ai injection ranked first place for two consecutive years,and these index present a great increasing trend.In 2013,its constituents ratio reached up to 85.09%.The consumption sum,constituents ratio,DDDs of Aidi injection had been greatly decreased.No significant changes were found in the DDC of four drug varieties.All the investigated anticancer TCM injection had a low incidence of adverse drug reactions.Conclusion Kang＇ai injection was predominant in the anticancer TCM injection,but the structure of drug usage was not reasonable.The drug regulation and supervision were still needed to be further strengthened.