猪繁殖与呼吸综合征的抗病育种研究进展

Research progresses on the breeding of anti PRRS( porcine reproductive and respiratory syndrome) pigs

猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)是近期危害养猪业最重要的疾病之一。培育抗病性品种是该病综合防治的一个有效方法。文章围绕该病抗病育种候选基因研究的主要进展进行综述,内容涉及病毒特异性受体基因、先天性免疫相关基因、抗原递呈信号通路相关基因、胞内miRNA等,并重点就今后PRRSV疾病耐受性和提高适应性免疫应答能力的研究进行展望。

Anti-disease breeding was effective on preventing infective disease in pigs. Recently,porcine reproductive and respiratory syndrome（PRRS） is severely impacted pig industry. Anti-PRRSV（porcine reproductive and respiratory syndrome virus,PRRSV） breeding would be an effective solution. In the present paper,research progress on candidate genes for anti-PRRSV breeding was summarized,including genes of virus receptor,innate immunology,antigen presentation signal pathway and miRNA. Moreover,further research focus on immune tolerance and adaptive immunology of PRRSV were suggested.