摘要
以邻氨基甲基苯酚与硝基取代苯甲醛为原料,在SnCl4的催化作用下合成了一系列取代-1,3-苯并噁嗪类化合物,产率为60%~95%.产物结构经IR、^1H NMR、^13C NMR、MS和元素分析进行了表征.测定了所合成化合物的杀虫活性,化合物对蚜虫具有较好的活性,其中2-(2-硝基苯基)-3-苯基-3,4-二氢-2H-1,3[e]-苯并噁嗪(5o)的活性达80% (500 mg/L).
A series of 1,3-benzoxazine derivatives were synthesized in 60%~95 % yields from the reaction of 2-arylaminomethylphenols and nitrobenzaldehyde in the presence of SnCl4.The structures of the target compounds were characterized by IR、^1H NMR、^13C NMR、MS and element analysis.The insecticidal activities of the title compounds were measured,the results showed that these compounds exhibited good insecticidal activities against Aphis fabae as shown by compound 5o with 80% activity at concentration of 500 mg/L.
出处
《华中师范大学学报(自然科学版)》
CAS
北大核心
2014年第5期677-683,共7页
Journal of Central China Normal University:Natural Sciences
基金
国家科技支撑计划项目子课题(2011BAE06B01)
湖南省高校创新平台开放基金项目(13K089)
理论化学与分子模拟省部共建教育部重点实验室开放基金项目(LKF1103)
关键词
1
3-苯并噁嗪
合成
杀虫活性
1,3-benzoxazine
synthesis
insecticidal activity