清热复脉汤联合美托洛尔治疗室性期前收缩的疗效观察

THERAPEUTIC EFFECTS OF QINGREFUMAI DECOCTION COMBINED METOPROLOL SUCCINATE IN TREATMENT OF VENTRICULAR PREMATURE CONTRACTION

目的:观察清热复脉汤联合美托洛尔对痰热型室性期前收缩(VPC)的疗效。方法:60例痰热型VPC患者随机分为治疗组和对照组,每组30例患者,对照组患者给予琥珀酸美托洛尔片口服,治疗组患者在对照组治疗的基础上给予清热复脉汤,每日一剂口服,两组的疗程均为3周。比较两组患者用药前后的疗效和VPC次数。结果:治疗后治疗组的临床总有效率和中医症候总有效率分别为80.0%、83.3%,均明显高于对照组(P<0.05)。治疗后两组患者VPC次数均明显减少,但治疗组的改善效果优于对照组(P<0.05)。结论:清热复脉汤联合美托洛尔对痰热型VPC有较好的疗效,并能显著改善患者的中医临床症候。

Objective：To observe the therapeutic effects of Qingrefumai decoction combined metoprolol succinate in treatment of ventricular premature contraction（VPC）.Methods：60 phlegm-heat type VPC patients were randomly divided into treatment group and control group,with 30 patients in each group.The patients in control group were only given metoprolol succinate;while the patients in treatment group were also given Qingrefumai decoction.The therapeutic effects and times of VPC of patients in 2 groups were compared after 3-week treatment course.Results：After treatment,the total clinical effective rate and TCM symptoms total effective rate of treatment group were respectively 80.0% and 83.3%,which were all obviously higher than that of control group（P 0.05）.After treatment,the times of VPC of patients in 2 groups were all decreased;moreover,the improving effects of treatment group was better than control group（P 0.05）.Conclusions：Treating VPC with Qingrefumai decoction combined metoprolol succinate can get better therapeutic effects;also can improve TCM symptoms signifi cantly.