期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

免疫微环境与肿瘤关系的研究进展 被引量：5

Research progress of immune microenvironment in tumors
原文传递
导出
摘要 近年研究表明,肿瘤组织中的免疫成分,如各类免疫细胞及其他间质细胞与肿瘤细胞产生的生长因子、细胞因子、促进血管生成因子等协同作用,促进了肿瘤的发生发展.文章就肿瘤免疫微环境和肿瘤发生发展的研究进展作一综述. Recent studies demonstrated that immune components including immune cell populations,growth factors,cytokines and angiogenic factors produced by stroma cells as well as tumor cells in tumor microenvironment cooperated with the promotion of the initiation and progression of tumors.In this paper,the research progress of immune microenvironment in tumors has been concluded.
作者 剧雪华 李光耀
机构地区 河北省藁城市人民医院肿瘤科
出处 《肿瘤研究与临床》 CAS 2014年第9期643-645,共3页 Cancer Research and Clinic
关键词 肿瘤 免疫微环境 Neoplasms Immune microenvironment
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献31

  • 1张百红,岳红云.肿瘤微环境与肿瘤[J].国际肿瘤学杂志,2013,40(8):582-584. 被引量：13
  • 2Schmid MC, Varner JA. Myeloid cell trafficking and tumor angiogenesis[J]. Cancer Lett, 2007, 250: 1-8.
  • 3Kryczek I, Wei S, Keller E, et al. Stroma-derived factor (SDF- 1/CXCL12) and human tumor pathogenesis [J]. Am J Physiol Cell Physiol, 2007, 292: C987-995.
  • 4Srikrishna G, Freeze HH. Endogenous damage-associated molecular pattern molecules at the crossroads of inflammation and cancer [J]. Neoplasia, 2009, 11: 615-628.
  • 5Porta C, Subhra Kumar B, Larghi P, et al. Tumor promotion by tumor- associated macrophages[J]. Adv Exp Med Biol, 2007, 604: 67-86.
  • 6Liao YP, Schaue D, McBride WH. Modification of the tumor microenvironment to enhance immunity[J]. Front Biosci, 2007, 12: 3576-3600.
  • 7Fukumura D, Kashiwagi S, Jain RK. The role of nitric oxide in tumour progression[J]. Nat Rev Cancer, 2006, 6: 521-534.
  • 8Sica A, Schioppa T, Mantovani A, et al. Turnout-associated macrophages are a dislinet M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy[J]. Eur J Cancer, 2006, 42: 717-727.
  • 9Allavena P, Sica A, Solinas G, et al. The inflammatory micro- environment in tumor progression: the role of tumor-associated macrophages[J]. Crit Rev Oncol Hematol, 2008, 66: 1-9.
  • 10李璘,邱蓉丽,乐巍,姚卫峰,余果.肿瘤微环境中的非肿瘤细胞[J].中国药理学通报,2012,28(4):455-457. 被引量：6

二级参考文献48

  • 1李璘,朱荃,陆茵.粘附分子与肿瘤转移[J].中国药理学通报,2007,23(5):568-571. 被引量：18
  • 2Grivennikov, S.I. Greten, F.R. Karin, M. Immunity, inflammation, and cancer[J]. Cell, 2010, 140(6): 883-899.
  • 3de Martel, C. Franceschi, S. Infections and cancer.. established associations and new hypotheses [J]. Crit Rev Oncol Hematol, 2009, 70(3): 183-194.
  • 4Biswas, S.K. Mantovarfi, A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm [J]. Nat Immunol, 2010, 11(10): 889-896.
  • 5Movahedi, K. Laoui, D., Gysemans, C., et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes [J]. Cancer Res, 2010, 70(14): 5728-5739.
  • 6Krausgruber, T. Blazek, promotes inflammatory TH 1-TH 17 responses [J]. 231-238 K., Smallie, T., et al. IRF5 macrophage polarization and Nat Immunol, 2011, 12 (3):.
  • 7Karin, M. Nuclear factor-kappaB in cancer development a- nd progression[J]. Nature, 2006, 441(7092): 431-436.
  • 8Nagaraj, S. Gabrilovich, D.I. Myeloid-derived suppressor cells in human cancer[J]. Cancer J, 2010, 16(4).. 348-353.
  • 9Yang, L. Huang, J. Ren, X., et al. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-I+CDllb+ myeloid cells that promote metastasis [J]. Cancer Cell, 2008, 13(1): 23-35.
  • 10Gabrilovich, D.I. Nagaraj, S. Myeloid-derived suppressor cells as regulators of the immune system [J]. Nat Rev Immunol, 2009, 9(3): 162-174.

共引文献20

同被引文献50

  • 1肖颖丽,梁志清,邱敏.卵巢上皮性癌中HIF-1α、COX-2表达和血管生成的关系[J].重庆医学,2005,34(10):1503-1505. 被引量：4
  • 2Little CC. The inheritance of cancer [ J ]. Science, 1915, 42 ( 1084 ) : 494-495.
  • 3Fukumura D, Jain RK. Tumor microvasculature and targets for anti-angiogenesis and normalization [ J ]. Microvasc Res, 2007 , 74 ( 2-3 ) : 72-84.
  • 4Tredan O, Galmarini CM, Patel K, et al. Drug resistance and the solid tumor microenvironment [ J ]. J Natl Cancer Inst, 2007, 99 ( 19 ) : 1441-1454.
  • 5Hashizume H, Baluk P, Morikawa S, et al. Openings between defective endothelial cells explain tumor vessel leakiness [ J ]. Am J Pathol, 2000, 156 ( 4 ) : 1363-1380.
  • 6Lindner D J, Raghavan D. Intra-tumoral extracellular pH: a useful parameter of response to chemotherapy in syngenic tumor lines [ J ]. BrJ Cancer, 2009, 100( 8 ) : 1287-1291.
  • 7Chen LQ, Howison CM, Jeffery JJ, et al. Evaluations of extracellular pH within in vivo tumors using acidoCEST MRI [ J ]. Magn Reson Med, 2014, 72( 5 ):1408-1417.
  • 8Kim KS, Park W, Hu J, et al. A cancer- recognizable MRI contrast agents using pH-responsive polymeric micelle [ J ]. Biomaterials, 2014, 35 ( 1 ) : 337-343.
  • 9Polyak K, Haviv I, Campbell IG. Co-evolution of tumor cells and their microenvironment [ J ]. Trends Genet, 2009, 25 ( 1 ) : 30-38.
  • 10Olive KP, Jacobetz MA, Davidson C J, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer[ J ]. Science, 2009, 324( 5933 ) : 1457-1461.

引证文献5

二级引证文献18

肿瘤研究与临床
2014年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部