转移性肾细胞癌的靶向治疗

Targeted therapy of metastatic renal cell cancer

抗血管生成治疗是转移性肾细胞癌的标准治疗。近年来，肿瘤新生血管通路的众多抑制剂纷纷进入临床研究，部分靶向药物取得良好的临床疗效。其他信号通路阻断剂如哺乳动物雷帕霉素靶蛋白与成纤维生长因子受体通路抑制剂也取得一定的成果。

Targeted therapy of anti-angiogensis strategy is the standard treatment for metastatic renal cell cancer.In recent years,a number of new generation of anti-angiogensis agents have been tested in clinical trials,some of which have achieved promising outcomes.Other pathway inhibitors such as inhibitors of mamma-lian target of rapamycin and fibroblast growth factor receptor pathway have made progresses in some extent.