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白细胞去除术联合化疗治疗高白细胞性白血病临床研究 被引量:1

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摘要 高白细胞性白血病(hyperleukocytic leukemia, HLL)指外周血白细胞(WBC)>100×109/L的白血病[1],因大量白血病细胞瘀滞,患者易发生高白细胞综合征、肿瘤溶解综合征、呼吸窘迫综合征及颅内出血等严重并发症,早期死亡率高。文献报道,白血病患者外周血WBC>50×109/L并伴有白细胞瘀滞症状或即使无症状但WBC >100×109/L,均应行紧急的细胞去除[2]。本院血液科于2012年8月至2013年12月应用COBE spectra血细胞分离机行白细胞去除术联合化疗治疗HLL患者26例,取得较好疗效,现回顾性分析如下。
出处 《国际肿瘤学杂志》 CAS 2014年第9期717-719,共3页 Journal of International Oncology
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