普米克令舒与孟鲁司特联合治疗56例小儿慢性咳嗽临床疗效

Clinical Effect of Using Pulmicort Respules and Montelukast to Cure 56 Cases with Chronic Cough in Children

目的：探讨普米克令舒联合孟鲁司特治疗小儿慢性咳嗽的临床疗效。方法：选取某院2013年12月-2014年4月收治的168例慢性咳嗽患儿作为研究对象,按照1：1：1比例分为3组,对照组（56例）给予综合性基础治疗,治疗组a（56例）在对照组基础上加用普米克令舒雾化吸入治疗,治疗组b（56例）给予普米克令舒雾化吸入＋孟鲁司特治疗,比较3组治疗效果。结果：经过14d的治疗后,对照组、治疗组a、治疗组b的总有效率分别为48.21%、69.64%、87.50%,治疗组b的总有效率明显高于对照组和治疗组a,差异有统计学意义（P〈0.05）;治疗组b的咳嗽频度和严重度明显低于对照组和治疗组a,具有统计学意义（P〈0.05）。结论：普米克令舒与孟鲁司特治疗小儿慢性咳嗽疗效显著,安全性高,对改善患儿的病情及预后有重要意义,值得临床广泛推广和应用。

Objective：This paper discusses clinical effect of using pulmicort respules and montelukast to cure chronic cough in children. Methods： A total of 168 children with chronic cough who received treatment in the hospital from December 2013 to April 2014 were selected as objects of this study. They were randomly divided into three groups on average, namely the control group （56 cases）, the treatment group a （56 cases） and the treatment group b（56 cases）. The control group are treated by comprehensive basic treatment;the treatment group a are treated by pulmicort respules inhalation therapy on the basis of the control group; the treatment group b are treated by pulmicort respules inhalation therapy and montelukast treatment. Compare clinical effects of the three groups. Results：After the 14-day treatment, the total effectiveness of the three groups are respectively 48.21%, 69.64% and 87.50%. The total effectiveness of treatment group b is obvious higher than that of control group and group a, and these differences are statistically significant （P＆lt;0.05）. The cough frequency and severity of treatment group b are obvious than those of control group and treatment group a. Conclusion： Pulmicort respules and montelukast treatment has obvious curative effect on chronic cough in children with high safety and significance towards prognosis and improving symptoms. It is worthy to be widely promoted and applied clinically.