河北省不同精神障碍患者药物使用现况调查

Cross-sectional study on drug patterns of mental disorder in Hebei province

目的分析2012年河北省不同精神障碍患者药物的使用情况。方法纳入2012年河北省在门诊和住院的3种常见精神障碍患者4221例,用自制问卷进行调查并进行分析。结果在精神分裂症患者中,69.2%接受单一药物治疗,30.8%联合使用2种及其以上抗精神病药,且住院患者联合用药比例明显高于门诊患者(P<0.01)。双相障碍患者中,87.3%用抗精神病药,76.4%用心境稳定剂,29.2%用苯二氮类药物;联用2种及其以上药物治疗的比例占82.5%。在抑郁症患者中,95.6%接受抗抑郁药治疗,合并药物主要是苯二氮类药物(41.4%)。结论河北省3种常见精神障碍患者的药物处方方式基本合理。

Objective To analyse the medication treatment patterns of mental disorder in Hebei province in 2012. Methods A total of the 4221 patients inciuding outpatient and inpatient, who were diagnosed with schizophrenia, bipolar mania and depression from Hebei province were selected and investigated with self-made questionnaire. Results The 69.2% patients of schizophrenia were treated with mono - pharma- cy 30. 8% were treated with at least two antipsychotics. More inpatients use combined antipsych0tics than outpatients （P 〈 0. 01 ）. The 87. 3% patients of bipolar disorder were treated with antipsychotic agents, 76. 4% with mood stabilizers, 29.2% with the benzodiazepine. And most of the bipolar disorder patients （82. 5% ） were treated with psychiatric medications. The 95.6% patients of depression were treated with antidepressants. The cOmmon concomitant medication were benzodi- azepine （41.4%）. Conclusion The drug patterns of schizophrenia, bipolar disorder and depression in Hebei province are rational.