pH响应的层层自组装(LBL)微胶囊和多层薄膜研究

pH-responsive layer-by-layer assembly(LBL)microcapsules and multilayer films

首先简述了一种新颖的制备微胶囊和薄膜的方法-层层自组装法(LbL),LbL法制备微胶囊和薄膜的显著优越性在于能够在纳米尺度上对微胶囊和薄膜的组成、结构、形态和厚度进行精确的控制。然后,详细介绍了pH响应的微胶囊和薄膜的制备、对某些物质的包埋以及释放。pH值的改变会引起薄膜和微胶囊通透性的变化,甚至导致薄膜与微胶囊的分解,从而释放内部比如蛋白、多肽等物质。最后,对微胶囊和薄膜的应用前景做了简单的展望。

A novel preparing method of microcapsules and films-layer-by layer assembly method（LBL）was firstly present. The significant advantage of LbL films and LBL microcapsules was that the thickness, size, composition, construction and shape can be regulated precisely at the nanometer level by simply changing the number of deposited layers. Then, the pH-responsive microcap- sules and thin films,as well as the release of certain embeded substances were detailed, pH-induced decomposition or permeability changes of LbL films and microcapsules formed the basis for the release of some substances, such as proteins or peptides. Finally a simple outlook of the application of the LBL microcapsules and LBL films was did.