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CpG-ODN疫苗佐剂的研究进展 被引量：3

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摘要 含胞嘧啶-鸟嘌呤（CpG）二核苷酸的寡聚脱氧核苷酸链（CpG-ODN）是一种具有巨大开发潜力的佐剂,这是一类合成的、包含有1个或多个非甲基化的CpG基序的单链DNA。研究表明,CpG-ODN能够选择性地增强脊椎动物的细胞和/或体液免疫应答,有效提升多种疫苗的免疫效果。
作者 张庆勇 罗春华 朱武飞
机构地区 三峡大学第一临床医学院宜昌市中心人民医院检验科
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2014年第10期1416-1418,共3页 Chinese Journal of Immunology
基金 国家自然科学基金青年基金(81202303)资助项目
关键词 疫苗佐剂 CPG-ODN 体液免疫应答 树突状细胞 抗原提呈 巨噬细胞 免疫效应细胞 基序 细胞毒活性 细胞因子
分类号 R392.5 [医药卫生—免疫学]
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参考文献25

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二级参考文献34

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中国免疫学杂志
2014年 第10期

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