摘要
目的研究椴树科椴树属植物紫椴Tilia amurensis Rupr.干燥花序的化学成分。方法采用硅胶、ODS、Sephadex LH-20柱色谱及制备HPLC等方法进行分离,采用理化分析及NMR、MS等波谱学方法鉴定化合物结构。结果从紫椴花70%乙醇提取物醋酸乙酯部位分离得到14个化合物,分别鉴定为蒙花苷(1)、异槲皮苷(2)、槲皮素(3)、紫云英苷(4)、银椴苷(5)、5,7,4′-三羟基-3′-甲氧基异黄酮(6)、香豌豆酚(7)、槲皮素-3-O-α-L-吡喃阿拉伯糖苷(8)、木栓酮(9)、β-谷甾醇(10)、原儿茶酸(11)、茶碱(12)、咖啡因(13)、棕榈醇(14)。结论化合物1~5、7、8、10~12为首次从该植物中分离得到,化合物7为首次从椴树属植物中分离得到。
Objective To study the chemical constituents from the inflorescences of Tilia amurensis. Methods The chemical constituents were separated and purified by silica gel, Sephadex LH-20, ODS column chromatographies, and preparative HPLC. Their structures were determined by physicochemical properties and spectral data. Results Fourteen compounds were isolated from the ethyl acetate fraction of 70% ethanol extract in the inflorescences of T. amurensis, and identified as linarin(1), soquercitrin(2), quercetin(3), astragalin(4), tiliroside(5), 5, 7, 4′-trihydroxy-3′-methoxy isoflavone(6), orobol(7), quercetin-3-O-α-Larabinopyranoside(8), friedelin(9), β-sitosterol(10), protocatechuic acid(11), theophylline(12), caffeine(13), and palm alcohol(14). Conclusion Compounds 1—5, 7, 8, and 10—12 are isolated from this plant for the first time, and compound 7 is found in the plants of Tilia Linn. for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2014年第17期2453-2456,共4页
Chinese Traditional and Herbal Drugs
基金
哈尔滨市科技创新人才基金(2013RFXXJ027)
黑龙江中医药大学优秀创新人才支持计划项目(2012RCQ15)