福建省畲族人群睡眠质量与2型糖尿病的研究

Relation between sleep quality and diabetes in the She ethnic minority group in Fujian province,China

目的：探讨中国福建省畲族人群睡眠质量与糖尿病患病的关系。方法采取横断面、多阶段、年龄和性别分层抽样的方法抽取福建省畲族不同村居民共5358人进行睡眠质量问卷调查，并抽血行相关指标检验。结果调查对象的睡眠质量差总患病率为4.5%。而睡眠质量好的人群中糖尿病患病率为5.9%，睡眠质量差的人群中糖尿病患病率高，为16.7%，睡眠质量好的人群中糖尿病患病率明显低于睡眠质量差的患者（χ2＝116.29，P＜0.001）；两因素相关分析显示PSQI积分和血糖水平呈正相关，调整混杂因素后结果显示睡眠质量是糖尿病发病的独立危险因素[OR＝1.722，95%confidence interval（CI）＝1.137-2.607，P＝0.01]。结论福建畲族人群睡眠质量差的人糖尿病患病率较高，应重视睡眠质量差的人群的睡眠障碍的治疗及预防，以降低糖尿病患病率。

Objective To analyze the relation between sleep quality and diabetes in the She ethnic minority group in Fujian province. Methods This study is a cross-sectional survey. Subjects completed a questionnaire collecting demographic and each patient completed the Chinese version of the Pittsburgh Sleep Quality Index （PSQI） questionnaire. Physical examination and clinical laboratory tests were performed. Data were analyzed by regression analysis. Results A total of 5 358 participants entered into the analysis. After adjusting for age, gender and body mass index, the total PSQI score （P〈0.001） were significantly correlated with blood glucose. Logistic regression analysis showed the adjusted odds ratio （OR） of PSQI score for blood glucose level was 3.178[OR=3.178, 95% confidence interval （CI）=2.213-4.564, P〈0.001]. The adjusted OR of worse glycaemic control for the poor sleep quality group was 1.722 with regard to the group of good sleep quality （OR=1.722, 95% CI=1.137-2.607, P=0.01）. Conclusions This study demonstrate that poor sleep quality is significantly correlated with worse glycaemic control in patients with type 2 diabetes.