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含左氧氟沙星三联疗法根除幽门螺杆菌的疗效观察 被引量:1

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摘要 目的观察质子泵抑制剂(PPi)、可乐必妥、阿莫西林三联疗法根除幽门螺杆菌的疗效。方法将60例感染HP患者随机分为治疗组和对照组,治疗组采用PPI、可乐必妥、阿莫西林治疗,对照组采用PPI、克拉霉素、阿莫西林治疗,疗程7天。治疗结束4~6周后观察幽门螺杆菌根除率、不良反应等。结果治疗组失访3例,对照组失访4例,治疗组和对照组对幽门螺杆菌的根除率分别为88.9%和65.4%,差异具有统计学意义(P〈0.05);对照组1例发生严重不良反应(药疹),经治疗后缓解。结论含左氧氟沙星三联疗法可获得较高的幽门螺杆菌根治率,且不良反应发生率低,是理想的治疗方案。
作者 王飞
出处 《常州实用医学》 2014年第5期291-293,共3页 CHANGZHOU PRACTICAL MEDICINE
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参考文献9

  • 1Gisbert JP, Gonzalez L, Calvet X.Systematic review and meta - analysis: proton pump inhibitor vs. ranifidine bismuth citrate plus two antibiotics inHelicobacter pylofi? eradication [ J] . Helicobacter, 2005,10(3) : 157 - 71.
  • 2邹军,杨昭徐,唐明忠,康熙雄.幽门螺杆菌对4种抗菌药物的敏感性检测及意义[J].临床检验杂志,2003,21(4):219-220. 被引量:20
  • 3Liu HH. Safety prof'de of the fluoroquinolones: focus on lev- ofloxaein[J]. Drug Saf,2010,33(5) :353 - 369.
  • 4Bhavnani SM1, Andes DR. Gemifloxacin for the treatment of respiratory tract infections:in vitro susceptibility, phammcoki- netics and pharmacodynamics, clinical efficacy, and safety [J]. Pharmacotherapy,2005,25(5):717 - 740.
  • 5陈炎,陈亚蓓,陶荣芳.左氧氟沙星三联疗法根除幽门螺杆菌感染106例[J].中国新药与临床杂志,2002,21(7):437-439. 被引量:18
  • 6沈兰兰,刘文忠,萧树东.1997年亚太地区关于幽门螺杆菌感染处理的共识[J].中华内科杂志,1998,37(9):633-635. 被引量:31
  • 7张万岱,徐智民.Hp耐药现状[J].中华消化杂志,2003,23(9):556.
  • 8Luther J1, Higgins PD, Schoenfeld PS, Moayyedi P, Vakil N, Chey WD.Empiric quadruple vs. triple therapy for primary treatment of Hellcobacter pylori infection: Systematic review and meta- analysis of etcaey and tolerability [ J ]. Am JGastroenteml, 2010,105 ( 1 ) : 65 - 73.
  • 9Di Cam S1, Fini L, Daoud Y, Grizzi F, Gasbzini A, De Lorenzo A, Di Renzo L, McCamaey S, Bloom S. Levofloxaein/ amoxicillin- based schemes vs quadruple therapy for He- licobacter pylori eradication in second - line [ J]. World J Gastroenterol,2012,18(40) :5669 - 5678.

二级参考文献13

  • 1赵庆卫.幽门螺杆菌研究现状[J].中国医学文摘:内科学分册,1999,20(6):702-704.
  • 2Georgopoulos S D, Ladas S D, Karatapanis S, et al. Factors that may affect treatment outcome of triple Helicobacter priori eradication therapy with omeprazole, amoxicillin, and clarithromycin [ J ]. Dig Dis Sci, 2000, 45(1):63-67.
  • 3Piccolomini R,Bonavenura G D,Catamo,et al.Comparative eveluation of the E test,agar dilution,and broth microdilution for testing susceptibilities of Helicobacter pylori strains to 20 antimicrobial agents[J].J Clin Microbiol,1997,35(7):1842-1846.
  • 4Pfaller M A,Barry A L, Fuchs P C. et al. Levofloxacin disk potency and tentative intexpretive criteria for susceptibility tests[J]. J Clin Microbiol, 1993,31(7):1924-1926.
  • 5van der Wouden E J, Thijs J C, van Zwet A A, et al. Nitrointidazole resistance in Helicobacter pylori[J]. Aliment Pharmaed Ther, 2000, 14 (1):7-14.
  • 6Boyanova L, Stancheva I, Spassova Z, et al. Primary and combined resistance to four antimicrobial agents in Helicobacter pylori in Sofia,Bulgaria[J] .J Med Microbiol,2000,49(5):415-418.
  • 7Ducons J A, Sentolaria S, Guirao R, et al. Impact of clarithromycin resistance on the effectiveness of a regimen for Helicobacter pylori: a prospective study of 1-week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer[J].Aliment Pharmacol Ther, 1999, 13(6):775-780.
  • 8Yakoob J, Fan X, Hu G,et al. Antibiotic susceptibility of Helicobacter pylori in the Chinese population[J] .J Gastroenterol and Hepatol,2001,16 (9) :981-985.
  • 9胡品津,李瑜元,陈湖,吴惠生,崔毅,黎庆宁.克拉霉素、甲硝唑和兰索拉唑联合治疗幽门螺杆菌感染的临床疗效观察[J].中华消化杂志,1997,17(4):204-206. 被引量:54
  • 10赵本钰,林菁,张伟,程国利.消化性溃疡抗感染治疗[J].中国新药与临床杂志,1998,17(1):49-50. 被引量:33

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