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麻醉深度对体外循环脑损伤的影响 被引量:1

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摘要 目的:探讨麻醉深度对体外循环脑损伤的影响。方法:选取医院收治的体外循环下行瓣膜置换术的患者64例作为研究对象,根据麻醉深度的不同,分为A、B两组,每组32例,比较两组患者麻醉前后的血浆S-100β蛋白水平、血气分析结果、脑氧供情况等。结果:A组在T1时刻的AVDO2、CEO2水平均显著低于B组(P<0.05)。A组T2、T3时刻的血清S-100β蛋白均显著低于B组(P<0.05)。两组患者术前1d的MMSE评分比较无显著差异(P>0.05),A组术后1d的MMSE评分显著高于B组(P<0.05)。结论:不同的麻醉深度会对体外循环脑损伤造成不同的影响,较深麻醉可发挥一定的脑保护作用,临床上可根据BIS监测值控制麻醉深度,以减少体外循环脑损伤。
作者 蒋迅
出处 《长江大学学报(自科版)(下旬)》 CAS 2014年第9期52-53,57,共3页 Journal of Yangtze University
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