摘要
免疫系统与抗原接触,产生对其初次的特异性应答;当免疫系统再次与该抗原接触时,通常会产生再次应答;这一现象称之为免疫的记忆性。在抗感染免疫方面,免疫记忆现象的存在可以防止同一疾病的再次发生,对人体产生保护作用,这也是预防接种的免疫基础。但免疫记忆对人体不只有保护作用,在某些情况下也会对人体产生负面影响。本文就免疫记忆现象在抗感染免疫,肿瘤免疫,移植免疫,以及自身免疫性疾病和变态反应性疾病等方面对人体的正反两方面作用进行综述。深入研究其负面作用,可能为免疫相关性疾病的发生,发展及治疗研究展开一个全新的视界。
Primary specific immunological response occurs when the immune system meets antigen for the first time,and secondary specific immunological response happens when the immune system meets the same antigen,this phenomenon is called immune memory.Immune memory could protect us from the recurrence of the same infectious disease and this is the immunological base of immunization,but immune memory could also harm us in some special situations.In this article,we reviewed the positive and negative effects of immune memory on us in anti-infection immunity,tumor immunity,transplantation immunity,autoimmunity diseases and allergic diseases.Study in depth on the negative effect of immune memory will open a new door on understanding the occurrence,development and treatment of Immune-related diseases.
出处
《中华临床免疫和变态反应杂志》
2014年第3期228-232,共5页
Chinese Journal of Allergy & Clinical Immunology
