摘要
目的:评价走罐疗法治疗血瘀证斑块状银屑病的有效性和安全性。方法:将新疆维吾尔自治区中医药研究院、焉耆县人民医院皮肤科门诊及病房符合纳入标准的200例血瘀证斑块状银屑病患者采用计算机随机分组法按照1∶1∶1∶1的比例随机分配到平行的4组中,每组50例。安慰组模拟走罐、治疗1组走罐10次、治疗2组走罐30次、治疗3组走罐50次。在治疗1周、2周、3周时对患者皮损进行PASI评分(银屑病面积与严重程度评分),观察不良反应,进行统计分析。结果:试验最终纳入186例患者,脱落14例,治疗前后,治疗组与安慰组银屑病面积严重程度指数(PASI)评分相比具有显著性差异(P<0.01),各组治疗前后的PASI评分具有显著性差异(P<0.01);治疗组组间对PASI评分的影响无显著性差异。结论:走罐疗法是治疗血瘀证斑块状银屑病的一种安全有效的外治方法,临床推荐30次为走罐疗法的频次。但本研究的局限性在于基础干预措施较多,混杂因素不易控制,某些混杂因素可能会夸大或掩盖所研究的结果。
Objective: To evaluate the effectiveness and safety of the moving cupping therapy on plaque psoriasis in blood stasis syndrome. Methods: Two hundred cases of plaque psoriasis in blood stasis syndrome from the outpatient and ward of Dermatology Department in Xinjiang Uygur Autonomous Region Academy of Chinese Medicine and People's Hospital of Yanqi County who met the inclusion criteria, were randomly assigned to 4 groups according to 1∶1∶1∶1 by computer randomization, 50 cases in each group. The simulation moving cupping was conducted in the placebo group, while the moving cupping therapy was conducted in the treatment group A for 10 times, the treatment group B for 30 times, the treatment group C for 50 times. The psoriasis area and severity index(PASI) was scored at the 1st, 2nd and 3rd week of the treatment, and the adverse effect was observed for statistical analysis. Results: The trial included 186 cases finally, and fell of 14 cases. Before and after the treatment,PASI had significant difference between the treatment groups and placebo group(P〈0.01), and PASI in each group showed significant difference before and after the treatment(P〈0.01). However, there was no significant difference between the treatment groups. Conclusion: The moving cupping therapy is a kind of external treatments with effectiveness and safety for the treatment of plaque psoriasis in blood stasis syndrome. The frequency of moving cupping therapy is recommended as 30 times in clinic. In this study, the limitation is that there are many basis interventions, so that the confounding factors are harder to be controlled, which might exaggerate or cover up the results of this research.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2014年第10期3343-3345,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
新疆维吾尔自治区科技支撑计划(No.201133125)~~
关键词
走罐疗法
斑块状银屑病
血瘀证
Moving cupping therapy
Plaque psoriasis
Blood stasis