扶脾丸治疗脾胃虚寒型脱肛31例

Effect of Fupi Wan in 31 Cases with Rectal Prolapse

目的:探讨记载扶脾丸治疗脾胃虚寒型直肠脱垂的临床疗效。方法:将62例门诊确诊为脾胃虚寒型直肠脱垂的患者,随机按住院前后顺序分为扶脾丸组和对照组各31例。对照组给予黏膜下点状注射,扶脾丸组予中药内服及中药熏洗,治疗10 d后观察排便频率、排便时间、肛门脱出、排粪造影等指标比较疗效。结果:扶脾丸组治愈率高于对照组(P<0.05),扶脾丸组有效率高于对照组(P<0.05);两组治疗前后症状总积分比较,均有明显下降(P<0.05),扶脾丸组治疗后症状总积分下降比对照组明显(P<0.05);治疗后两组排便频率、排便时间、肛门脱出情况、排粪造影明显优于治疗前(P<0.05),扶脾丸组改善程度优于对照组(P<0.05);两组肛门坠胀感积分与治疗前比较明显降低(P<0.01),扶脾丸组改善情况优于对照组(P<0.05);两组排便不尽感积分与治疗前比较明显降低(P<0.01),扶脾丸组改善情况优于对照组(P<0.05);两组静息压与治疗前比较明显改善(P<0.05),两组治疗后比较无明显差异;两组缩榨压与治疗前比较无明显改善;两组排便压与治疗前比较有明显下降(P<0.01)。结论:中药内服扶脾丸结合中药熏洗对脾胃虚寒型直肠脱垂患者临床治疗有较好的治疗作用。

Objective：To observe the clinical effect of Fupi pills in treating patients with proctoptosis of deficiency of spleen-yang type in Chiese medicial syndrome.Method：Sixty-two patients diagnosed proctoptosis of deficiency of spleen-yang were randomly divided into the Fupi pills group and the control group of 31 cases each.The patients in the control group received submucous-punctiform injection,while the patients in the Fupi pills group received traditional Chinese medicine by oral and fumigating-washing administration.The efficacy was evaluated by comparing the experiment indexes （defecation frequency,defecation time,proctoptosis degree,and defecography,etc.） after 10 day treatment.Result：The curative rate of the Fupi pills group was higher than the control group （P ＜ 0.05）.The total effective rate of the Fupi pills group was higher than the control group （P ＜ 0.05）.After 10 day treatment,the total symptom-score in both groups was significantly decreased （P ＜ 0.05）,which was lower in the Fupi pills group than that in the control group （P ＜ 0.05）.The indexes such as defecation frequency,defecation time,proctoptosis degree and defecography were improved after treatment （P ＜ 0.05）,and the improvement was better in the Fupi pills group （P ＜ 0.05）.The symptom-score of anal pendant expansion was significantly decreased after the treatment （P ＜ 0.01）,which was lower in the Fupi pills group when comparing with that in the control group （P ＜ 0.05）.After treatment,the symptom-score of incomplete evacuation was decreased （P ＜ 0.01）,which was lower in the Fupi pills group （P ＜ 0.05）.The rest pressure was improved in both groups after treatment （P ＜ 0.05）,no significant differenceswere shown between two groups.The maximal squeezing pressure had no significant improvement in both groups after treatment （P ＜ 0.05）.The defecation pressure was significantly decreased in both groups after treatment （P ＜ 0.01）.Conclusion：Fupi pills together with fuming-washing of Chinese herb medicine have a good effect on rectal prolapse.