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兰索拉唑三联疗法治疗胃溃疡66例 被引量:9

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摘要 目的:探讨分析运用兰索拉唑三联疗法治疗胃溃疡的临床效果.方法:本次研究选取于2009-03~2013-12因胃溃疡入我院接受治疗的患者66例,将其随机划分为观察组和对照组.观察组患者采用兰索拉唑三联疗法,即阿莫西林,克拉霉素以及兰索拉唑共同治疗.而对照组则是采用阿莫西林,克拉霉素以及雷尼替丁联合治疗.观察分析两组患者在接受治疗的临床疗效,分析兰索拉唑三联疗法治疗胃溃疡的临床疗效.结果:两组患者在经过治疗后,可以发现观察组患者的治疗效果要明显优于对照组.对照组中有8例患者出现不良反应(占24.24%),而观察组中,则有3例患者出现不良反应(占9.09%).结论:兰索拉唑三联疗法治疗胃溃疡疗效优良,且不良反应少,值得临床上的进一步研究,和推广使用。
作者 陈和军
机构地区 中山市三角医院
出处 《黑龙江医药科学》 2014年第5期112-112,114,共2页 Heilongjiang Medicine and Pharmacy
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  • 1周世蓉.兰索拉唑联合铝碳酸镁治疗反流性食管炎疗效观察[J].现代医药卫生,2007,23(11):1636-1637. 被引量:3
  • 2Zvyaga T,Chang SY,Chen C ,et al. Evaluation of six proton pump inhibitors as inhibitors of various human cytochromes P450 : focus on cytochrome P450 2C19[J]. Drug Metab Dispos,2012,40(9) :1698-1711.
  • 3KuiPers EJ, Sung JJ, Barkun A, et a!. Safety and tolerability of highdose in- teravenous esomeprazole for prevention of peptic ulcer rebleeding [ J ]. Adv Ther,2011,28(2) :150-159.
  • 4Miura M, Tada H, Yasui-furukori N, et al antioselective disposition of Inasoprazole [J]. Chirality,2005,17(6) :338-344.
  • 5Effetc of clarithromycin on the en- in relation to CYP2C19 genotypes Takahashi K, Motohashi H,Yunezawa A,et al. Lansoprazole-tacrolimus interac- tion in Jpanese transplant recipient with CYP2CI9 polymorphism [J]. Ann Phar- macother ,2004,38 (5) :791-794.
  • 6Afeltra J,Vitale R G, Mouton J W, et al. Potent synergistic in vitro interaction between nonantimicrobial menbrane-active compounds and itraeonazole against elinnieal isolates of aspergillus fumigatus resistant to itraconazole[ J]. Antimi- crob Agents Chemother ,2004,48 (4) :1335-1343.
  • 7Yasui-furukori N, Saito M, Uno T, et al. Effects of fluvoxamine on Lanso- prazole pharmacokinetics in relation to CYP2C19 genotypes[ J]. J Clin phar- macol,2004,44( 11 ) : 1223-1229.
  • 8Small DS,Farid NA ,Payne CD,et al. Effects of the proton pump inhibitor lan- soprazole on the phamacokinetics and phamacodynamics of prasugrel and clo- pidogrel[ J]. J Clin Pharmacol 2008,48:475-484.
  • 9Juurlink DN,Gomes T,Ko DT,et al. A population-based study of the drug in- teraction between proton pump inhibitors and clopidogrel [ J]. CMAJ, 2009, 180:713-718.
  • 10Pauli-Magnus C,Rekembrink S,Klotz U,et al. Interaction of omeprazole,lan- soprasole and parttoprazole with P -glyeoprotein [ J ]. Naunyn Schmiedebergs Arch Phm'maeol,2001,364(6) :551.

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