比较口服达克罗宁胶浆与利多卡因胶浆在胃镜检查中的应用效果

Evaluation on efficiency of dyclonine mucilagines and lidocaine mucilagines in gastroscopy

目的 比较口服盐酸达克罗宁胶浆与盐酸利多卡因胶浆在胃镜检查过程中的效果.方法 将873例行胃镜检查的患者用随机方法分成观察组445和对照组428例.观察组胃镜检查前给予口服盐酸达克罗宁胶浆,对照组口服盐酸利多卡因胶浆,比较两组患者胃镜检查过程中恶心程度、插镜一次性成功率和检查后咽部疼痛的例数、视野清晰度、胃镜前端下至十二指肠降段及乳头部所需平均时间.结果 两组患者在胃镜检查过程中的恶心程度,一次插镜的成功例数,检查后咽部疼痛发生例数,视野清晰度,胃镜前端下至十二指肠降段及乳头部所需时间进行比较,差异均有统计学意义,观察组优于对照组（P均＜0.05）.结论 与盐酸利多卡因胶浆相比,盐酸达克罗宁胶浆口服在胃镜检查过程中祛泡效果明显,可显著提高视野清晰度;减轻恶心程度和检查后咽部疼痛,提高一次插镜的成功率,有效缩短检查所需的时间。

Objective To compare the effects of dyclonine mucilagines and lidocaine mucilagines on gastroscopy.Methods Eight hundred and seventy-three subjects were randomly divided into two groups,including 445 patients in observation group and 428 patients in control group.Patients in observation group received dyclonine mucilagines and patients in control group received lidocine mucilagines.The degree of nausea,the success rate of one-time intubation,the number of cases which had pharyngalgia after gastroscopy,clarity of vision and the average time the lens reached the descending and papilla part of duodenum was evaluated.Results The differences including the degree of nausea during gastroscopy,the number of one-time success intubations,the number of pharyngalgia cases,clarity of vision,the average time the lens reached the descending and papilla part of duodenum were statistical significant.The result of the observation group was better than that of the control group （P ＜ 0.05）.Conclusions Compared to lidocaine mucilagines,dyclonine mucilagines has significant antifoam effect and can improve the clarity of vision,mitigate the degree of nausea and pharyngalgia,improve the success rate of one-time intubations and reduce the time of gastroscopy.