急性中毒与抑郁症相关因素分析

Analysis of correlative factors of acute poisoning and depression

目的对急性中毒与抑郁症的相关因素进行分析。方法选择66例急性中毒患者,按中毒的原因是自主服毒还是误服分为自服组和误服组,按有无器质性疾病分为有器质性疾病组(包括糖尿病、脑梗死、结缔组织病、骨质疏松、COPD、脑外伤、肿瘤)和无器质性疾病组,采用汉密尔顿抑郁量表(HAMD)评定所有患者的抑郁症状。结果所有患者病情稳定后有抑郁症状者32例,占48.5%(32/66),其中男12例,占有抑郁症状者的37.5%,女20例,占有抑郁症状者的62.5%。自服组的HAMD评分高于误服组,差异有统计学意义(P<0.001);有器质性疾病组的HAMD评分高于无器质性疾病组,差异有统计学意义(P<0.001)。结论急性中毒以自主服毒为主,抑郁症与是否患器质性疾病有关。

Objective To analyze the correlative factors of acute poisoning and depression.Methods 66 cases of acute poisoning were divided into the group of taking poison on purpose and the group of taking poison by mistakes according to the causes of poisoning.In addition,they were divided into the group with organic diseases （including diabetes, cerebral infarc- tion, connective tissue disease, osteoporosis, COPD, brain trauma and tumor） and the group without organic diseases.Then, Hamilton Depression Rating Scale（HAMD） was used to evaluate the depressive symptoms of all patients.Results 32 cases had depressive symptoms after their condition was stable, accounting for 48.5% （32/66） .Of all patients with depressive symp- toms, there were 12 males, accounting for 37.5%, and 20 females, accounting for 62.5%.HAMD scores of the group of taking poison on purpose were significantly higher than those of the group of taking poison by mistakes, so the difference was statisti- cally significant（ P〈0. 001 ）.HAMD scores of the group with organic diseases were significantly higher than those of the group without organic diseases, so the difference was statistically significant （P〈0. 001 ）. Conclusion Acute poisoning is mainly caused by taking poison on purpose ,and depression is related to organic diseases.