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新生儿乳糜胸二例 被引量:2

Two cases of neonatal chylothorax
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摘要 新生儿乳糜胸是由胸导管或胸腔淋巴管破裂使淋巴液漏入胸腔所致,可引起严重呼吸困难及营养、免疫障碍,病死率较高。该文报道2例新生儿乳糜胸病例,2例均以呼吸困难、胸腔积液为主要临床表现,胸腔积液淋巴细胞比率均不低于0.8。1例经胸腔穿刺引流术联合一般治疗治愈,1例经阿奇霉素胸膜固定术治愈。2例成功诊治的经验提示临床医师应提高对该疾病的诊治水平,早诊断、及时处理有助于提高该病患儿的生存率。 Neonatal chylothorax is an uncommon form of pleural effusion caused by thoracic duct or pleural lymphatic rupture,probably leading to severe dyspnea,malnutrition,and immune dysfunction and rela-tively high mortality.This paper reported 2 cases of neonatal chylothorax.Main clinical manifestations included postpartum dyspnea and pleural effusion with a lymphocyte ratio greater than 0.8.One patient was cured by thoracentesis combined with routine treatment and 1 was healed by azithromycin pleurodesis.Successful experi-ence in this study promoted the clinicians to enhance the levels of diagnosis and treatment.Early diagnosis and timely therapy is beneficial to improve the survival of neonatal chylothorax.
出处 《新医学》 2014年第10期695-698,共4页 Journal of New Medicine
关键词 新生儿乳糜胸 胸腔穿刺术 胸膜固定术 Neonatal chylothorax Thoracentesis Pleurodesis
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参考文献6

  • 1Yeang CH, Ma GC, Shih JC, et al. Genome-wide gene expression analysis implicates the immune response and lymphangiogenesis in the pathogenesis of fetal chylotho- rax. PLoS One, 2012, 7: e34901.
  • 2Miyoshi T, Katsuragi S, Ikeda T, et al. Retrospectivereview of thoracoamniotic shunting using a double-basket catheter for fetal chylothorax. Fetal Diagn Ther, 2013, 34 : 19-25.
  • 3Leung VK, Suen SS, Ting YH, et al. [ntrapieural injec- tion of 0K-432 as the primary in-utero treatment for fetal chylothorax. HongKongMedJ, 2012, 18: 156-159.
  • 4Kalay S, Oztekin O, Tezel G, et al. Octreotide treatment in a neonate with non-chylous pleural effusion. Mr J Pae- diatr Surg, 2013, 10: 374-376.
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