氧气直接氧化苯制备苯酚

Direct Oxidation of Liquid Benzene to Phenol with Molecular Oxygen

苯酚是重要的化工原料,其工业生产主要是通过异丙苯氧化法制备,该方法存在制备流程长、消耗丙烯多以及产生大量副产物等不足。苯直接氧化制备苯酚,特别是氧气直接氧化苯制备苯酚,因其步骤少、操作成本低、环境友好等特点已成为苯酚绿色制备的研究热点。本文较为系统地总结了氧气氧化苯液相法合成苯酚的研究工作,综述了该反应体系下的反应机理以及所使用的催化剂、还原剂等;归纳了反应温度、反应压力、还原剂用量及反应溶剂等反应条件对苯酚产率的影响;分析了目前氧气直接氧化苯液相法制苯酚研究中存在的问题,并总结了未来的研究方向。

Phenol is a kind of important chemical materials, which is mainly produced from isopropylbenzene oxidation process. The drawbacks of the process include long synthesis process, consuming propylene and forming byproducts. Directly oxidation of benzene to phenol with molecular oxygen, possessing the advantages of less steps, low cost and environmental friendly, has become the research hotspot in green preparation of phenol. In this review, the progress of oxidation of liquid benzene to phenol with oxygen is summarized systematically. The reaction system, including the reaction mechanism, catalysts, and reductant is reviewed. The effects of reaction temperature, oxygen pressure, reductant and solvent on the yields of phenol are also discussed. Furthermore, the current research problems and future research perspectives are also suggested.