摘要
目的:探讨2型糖尿病视网膜病变(diabetic retinopathy,DR)的相关危险因素。方法:选择2012年10月—2013年8月行眼底检查的糖尿病患者253例,采用Logistic回归分析DR的相关危险因素。结果:253例糖尿病患者中,DR患者77例(30.43%),DR组与非DR组相比,年龄、病程、收缩压(systolic blood pressure,SBP)、尿微量白蛋白(urine microalbumin,U-MA)、UMA与尿肌酐(urine creatinine,UCr)比值的差异均有统计学意义(P<0.05)。Logistic回归分析显示,糖尿病病程是DR的独立危险因素(OR=1.191,P<0.005)。77例DR患者中,单纯DR患者65例,增殖期DR患者12例,两组总胆固醇(total cholesterol,TC)、U-MA、U-MA/UCr差异均有统计学意义(P<0.05)。结论:DR与年龄、病程、SBP、U-MA、U-MA/UCr等因素有关,糖尿病病程是DR的独立危险因素。
Objective: To explore the risk factors related to diabetic retinopathy (DR) in type 2 diabetic mellitus patients. Methods:From October 2012 to August 2013, 253 patients with type 2 diabetic mellitus were examined by fundoscopy. Logistic regression analysis was used to evaluate the related risk factors to DR. Results: There were 77 patients (30.43%) with DR in 253 DM patients. The differences of age, diabetic duration, systolic blood pressure (SBP), urine microalbumin (U-MA), and the ratio of U-MA to urine creatinine (UCr) were statistically significant between DR group and non-DR group (P〈0.05). Logistic regression analysis showed that diabetic duration was an independent risk factor related to DR (OR = 1.191, P〈0.005). There were 65 patients with non-proliferative DR and 12 patients with proliferative DR. The above groups had statisti- cally different total cholesterol (TC), U-MA and U-MA/UCr (P〈0.05). Conclusions: DR is correlated to age, diabetic dura- tion, SBP, U-MA and U-MA/UCr, in which diabetic duration is an independent risk factor related to DR.
出处
《中国临床医学》
2014年第3期343-345,共3页
Chinese Journal of Clinical Medicine