小剂量阿司匹林和肝素配伍治疗胎儿生长受限的疗效

The clinical efficacy of combination of low-dose aspirin and heparin on fetal growth restriction

目的探讨小剂量阿司匹林和肝素配伍治疗胎儿生长受限(FGR)疗效。方法随机将144例诊断为FGR患者分为两组,观察组84例在一般治疗基础上加予小剂量阿司匹林和肝素配伍治疗,对照组60例仅予一般治疗,观察两组疗效。结果小剂量阿司匹林和肝素配伍治疗FGR疗效显著高于对照组,无明显不良反应,治愈率高,结论小剂量阿司匹林和肝素配伍治疗FGR效果好,无明显不良反应,特别适合于基层医院推广。

Objective：To investigate the clinical efficacy of combination of low - dose aspirin and heparin on fetal growth restriction（FGR）. Methods：All 144 cases of FGR patients in our hospital were randomly divided into two groups：the ex-perimental group（n = 84）was treated with combination of low dose aspirin and heparin on the basis of traditional treat-ment,while the control group（n = 60）was treated only with traditional drugs. Then the clinical efficacy between the two groups were compared. Results：The clinical efficacy of low dose aspirin combination with heparin was significantly（P ﹤0. 05）greater than that of control group,which was combined with no obvious adverse effect and high cute rate. Conclu-sions：The clinical efficacy of low dose aspirin combination with heparin was satisfactory with no observed adverse effect. It is worth for clinical promotion in basic level hospital.