超声导向经会阴穿刺冷冻治疗中晚期前列腺癌

Ultrasound guided puncture in the treatment of advanced perineal prostate cancer

目的对超声导向经会阴穿刺冷冻治疗中晚期前列腺癌的效果进行探讨分析。方法对我院22例中晚期前列腺癌患者实施经会阴穿刺液氮冷冻前列腺肿瘤组织,对比穿刺前后PSA、前列腺及肿瘤体积的影像学结果。结果术后3个月患者的瘤体已经基本消失,仅残留少量的瘢痕组织。前列腺体积由术前的(64.3±4.8)ml降至(25.6±3.2)ml,PSA术前为(39.1±10.7)ng/ml,术后12个月、24个月时分别为(3.9±1.7)和(3.1±1.4)ng/ml。患者于术后6个月之前进行前列腺多点穿刺进行活检,2例患者为阳性。所有患者均未出现相关的冷冻并发症。结论超声导向经会阴穿刺冷冻治疗中晚期前列腺癌的效果比较理想,在临床上值得推广应用。

ObJective：To stuy the effect of ultrasound guided perineal puncture in the treatment of advanced prostate cancer. Methods：The advanced prostate cancer patients of 22 cases in our hospital had implementation of transperineal puncture cryotherapy prostate tumor tissue. PSA,puncture prostate and volume of tumor imaging results were compared. Results：The volume of prostate decreased from（64. 3 ± 4. 8）ml preoperative to（25. 6 ± 3. 2）ml. The preoperative value of PSA was（39. 1 ± 10. 7）ng/ ml,and droped to（3. 9 ± 1. 7）and（3. 1 ± 1. 4）ng/ ml,respectively in the 12,24 months after operation. Postoperative biopsies were positive only in two cases in the 6th months. Frozen related complications were not seen in all the patients. Conclusion：Ultrasound guided transperineal puncture in the treatment of advanced prostate cancer effect is relatively good,and is worthy of clinical application.